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A holin/peptidoglycan hydrolase-dependent protein secretion system.
Palmer T, Finney AJ, Saha CK, Atkinson GC, Sargent F. Palmer T, et al. Among authors: atkinson gc. Mol Microbiol. 2021 Mar;115(3):345-355. doi: 10.1111/mmi.14599. Epub 2020 Oct 12. Mol Microbiol. 2021. PMID: 32885520 Free article. Review.
ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life.
Murina V, Kasari M, Takada H, Hinnu M, Saha CK, Grimshaw JW, Seki T, Reith M, Putrinš M, Tenson T, Strahl H, Hauryliuk V, Atkinson GC. Murina V, et al. Among authors: atkinson gc. J Mol Biol. 2019 Aug 23;431(18):3568-3590. doi: 10.1016/j.jmb.2018.12.013. Epub 2018 Dec 28. J Mol Biol. 2019. PMID: 30597160 Free PMC article.
A widespread toxin-antitoxin system exploiting growth control via alarmone signaling.
Jimmy S, Saha CK, Kurata T, Stavropoulos C, Oliveira SRA, Koh A, Cepauskas A, Takada H, Rejman D, Tenson T, Strahl H, Garcia-Pino A, Hauryliuk V, Atkinson GC. Jimmy S, et al. Among authors: atkinson gc. Proc Natl Acad Sci U S A. 2020 May 12;117(19):10500-10510. doi: 10.1073/pnas.1916617117. Epub 2020 Apr 28. Proc Natl Acad Sci U S A. 2020. PMID: 32345719 Free PMC article.
A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains.
Kurata T, Saha CK, Buttress JA, Mets T, Brodiazhenko T, Turnbull KJ, Awoyomi OF, Oliveira SRA, Jimmy S, Ernits K, Delannoy M, Persson K, Tenson T, Strahl H, Hauryliuk V, Atkinson GC. Kurata T, et al. Among authors: atkinson gc. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2102212119. doi: 10.1073/pnas.2102212119. Proc Natl Acad Sci U S A. 2022. PMID: 35121656 Free PMC article.
The structural basis of hyperpromiscuity in a core combinatorial network of type II toxin-antitoxin and related phage defense systems.
Ernits K, Saha CK, Brodiazhenko T, Chouhan B, Shenoy A, Buttress JA, Duque-Pedraza JJ, Bojar V, Nakamoto JA, Kurata T, Egorov AA, Shyrokova L, Johansson MJO, Mets T, Rustamova A, Džigurski J, Tenson T, Garcia-Pino A, Strahl H, Elofsson A, Hauryliuk V, Atkinson GC. Ernits K, et al. Among authors: atkinson gc. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2305393120. doi: 10.1073/pnas.2305393120. Epub 2023 Aug 9. Proc Natl Acad Sci U S A. 2023. PMID: 37556498 Free PMC article.
Target protection as a key antibiotic resistance mechanism.
Wilson DN, Hauryliuk V, Atkinson GC, O'Neill AJ. Wilson DN, et al. Among authors: atkinson gc. Nat Rev Microbiol. 2020 Nov;18(11):637-648. doi: 10.1038/s41579-020-0386-z. Epub 2020 Jun 25. Nat Rev Microbiol. 2020. PMID: 32587401 Free article. Review.
55 results