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Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.
Sasako T, Ohsugi M, Kubota N, Itoh S, Okazaki Y, Terai A, Kubota T, Yamashita S, Nakatsukasa K, Kamura T, Iwayama K, Tokuyama K, Kiyonari H, Furuta Y, Shibahara J, Fukayama M, Enooku K, Okushin K, Tsutsumi T, Tateishi R, Tobe K, Asahara H, Koike K, Kadowaki T, Ueki K. Sasako T, et al. Among authors: asahara h. Nat Commun. 2019 Feb 27;10(1):947. doi: 10.1038/s41467-019-08591-6. Nat Commun. 2019. PMID: 30814508 Free PMC article.
Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway.
Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, Kaneko K, Kobayashi M, Iwane A, Sasako T, Okazaki Y, Ohsugi M, Takamoto I, Yamashita S, Asahara H, Akira S, Kasuga M, Kadowaki T. Awazawa M, et al. Among authors: asahara h. Cell Metab. 2011 Apr 6;13(4):401-412. doi: 10.1016/j.cmet.2011.02.010. Cell Metab. 2011. PMID: 21459325 Free article.
Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis.
Ito Y, Matsuzaki T, Ayabe F, Mokuda S, Kurimoto R, Matsushima T, Tabata Y, Inotsume M, Tsutsumi H, Liu L, Shinohara M, Tanaka Y, Nakamichi R, Nishida K, Lotz MK, Asahara H. Ito Y, et al. Among authors: asahara h. Nat Commun. 2021 Jul 6;12(1):4148. doi: 10.1038/s41467-021-24460-7. Nat Commun. 2021. PMID: 34230481 Free PMC article.
Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice.
Sasako T, Umehara T, Soeda K, Kaneko K, Suzuki M, Kobayashi N, Okazaki Y, Tamura-Nakano M, Chiba T, Accili D, Kahn CR, Noda T, Asahara H, Yamauchi T, Kadowaki T, Ueki K. Sasako T, et al. Among authors: asahara h. Nat Commun. 2022 Oct 5;13(1):5655. doi: 10.1038/s41467-022-33008-2. Nat Commun. 2022. PMID: 36198696 Free PMC article.
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.
Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H, Takayanagi H. Sato K, et al. Among authors: asahara h. Nat Med. 2006 Dec;12(12):1410-6. doi: 10.1038/nm1515. Epub 2006 Nov 26. Nat Med. 2006. PMID: 17128269
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H. Yokoyama S, et al. Among authors: asahara h. Dev Cell. 2009 Dec;17(6):836-48. doi: 10.1016/j.devcel.2009.10.011. Dev Cell. 2009. PMID: 20059953 Free PMC article.
Targeted gene deletion of miRNAs in mice by TALEN system.
Takada S, Sato T, Ito Y, Yamashita S, Kato T, Kawasumi M, Kanai-Azuma M, Igarashi A, Kato T, Tamano M, Asahara H. Takada S, et al. Among authors: asahara h. PLoS One. 2013 Oct 16;8(10):e76004. doi: 10.1371/journal.pone.0076004. eCollection 2013. PLoS One. 2013. PMID: 24146809 Free PMC article.
316 results