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Design and Synthesis of Novel 3-Nitro-1H-1,2,4-triazole-1,2,3-triazole-1,4-disubstituted Analogs as Promising Antitrypanosomatid Agents: Evaluation of In Vitro Activity against Chagas Disease and Leishmaniasis.
Pelizaro BI, Batista JCZ, Portapilla GB, das Neves AR, Silva F, Carvalho DB, Shiguemoto CYK, Pessatto LR, Paredes-Gamero EJ, Cardoso IA, Luccas PH, Nonato MC, Lopes NP, Galvão F, Oliveira KMP, Cassemiro NS, Silva DB, Piranda EM, Arruda CCP, de Albuquerque S, Baroni ACM. Pelizaro BI, et al. Among authors: arruda ccp. J Med Chem. 2024 Feb 22;67(4):2584-2601. doi: 10.1021/acs.jmedchem.3c01745. Epub 2024 Feb 2. J Med Chem. 2024. PMID: 38305199
Antileishmanial Activity, Toxicity and Mechanism of Action of Complexes of Sodium Usnate with Lanthanide Ions: Eu(III), Sm(III), Gd(III), Nd(III), La(III) and Tb(III).
da Silva F, Rizk YS, das Neves AR, Lourenço EMG, Ferreira AMT, Monteiro MM, de Lima DP, Perdomo RT, Bonfá IS, Toffoli-Kadri MC, Duarte AP, Nunes DM, Martines MAU, Piranda EM, de Arruda CCP. da Silva F, et al. Among authors: de arruda ccp. Int J Mol Sci. 2023 Dec 28;25(1):413. doi: 10.3390/ijms25010413. Int J Mol Sci. 2023. PMID: 38203584 Free PMC article.
Investigation of the Potential Targets behind the Promising and Highly Selective Antileishmanial Action of Synthetic Flavonoid Derivatives.
Lourenço EMG, da Silva F, das Neves AR, Bonfá IS, Ferreira AMT, Menezes ACG, da Silva MEC, Dos Santos JT, Martines MAU, Perdomo RT, Toffoli-Kadri MC, G Barbosa E, Saba S, Beatriz A, Rafique J, de Arruda CCP, de Lima DP. Lourenço EMG, et al. Among authors: de arruda ccp. ACS Infect Dis. 2023 Oct 13;9(10):2048-2061. doi: 10.1021/acsinfecdis.3c00336. Epub 2023 Sep 29. ACS Infect Dis. 2023. PMID: 37772925
Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituted isoxazole compounds based on benznidazole.
Carvalho DB, Costa PAN, Portapilla GB, das Neves AR, Shiguemoto CYK, Pelizaro BI, Silva F, Piranda EM, Arruda CCP, Gaspari PDM, Cardoso IA, Luccas PH, Nonato MC, Lopes NP, de Albuquerque S, Baroni ACM. Carvalho DB, et al. Among authors: arruda ccp. Eur J Med Chem. 2023 Nov 15;260:115451. doi: 10.1016/j.ejmech.2023.115451. Epub 2023 May 5. Eur J Med Chem. 2023. PMID: 37573209
In Vivo Antileishmanial Effect of 3,5-Diaryl-isoxazole Analogues Based on Veraguensin, Grandisin, and Machilin G: A Glance at a Preclinical Study.
das Neves AR, Carvalho DB, Silva F, Rosalem RF, Pelizaro BI, Castilho PF, Oliveira KMP, Cassemiro NS, Pessatto LR, Paredes-Gamero EJ, Piranda EM, Silva DB, Arruda CCP, Baroni ACM. das Neves AR, et al. Among authors: arruda ccp. ACS Infect Dis. 2023 May 12;9(5):1150-1159. doi: 10.1021/acsinfecdis.3c00090. Epub 2023 Apr 27. ACS Infect Dis. 2023. PMID: 37103973
Flavonoid Derivatives as New Potent Inhibitors of Cysteine Proteases: An Important Step toward the Design of New Compounds for the Treatment of Leishmaniasis.
Lourenço EMG, Di Iório JF, da Silva F, Fialho FLB, Monteiro MM, Beatriz A, Perdomo RT, Barbosa EG, Oses JP, de Arruda CCP, de Souza Júdice WA, Rafique J, de Lima DP. Lourenço EMG, et al. Among authors: de arruda ccp. Microorganisms. 2023 Jan 16;11(1):225. doi: 10.3390/microorganisms11010225. Microorganisms. 2023. PMID: 36677517 Free PMC article.
Morphometric vertebral fracture risk in women with postsurgical hypoparathyroidism.
d'Alva CB, Barreto ARF, Nogueira-Barbosa MH, Arruda CCC, Albuquerque ÁM, Praciano DMC, Viana RP, Gadelha DD, Viana AB Jr, Moreira IM, de Moura Filho FJR, Junqueira AFTA, Montenegro RM Jr. d'Alva CB, et al. Among authors: arruda ccc. Front Endocrinol (Lausanne). 2022 Dec 23;13:948435. doi: 10.3389/fendo.2022.948435. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36619538 Free PMC article.
23 results