Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 3
2004 5
2005 2
2006 5
2007 3
2008 3
2009 4
2010 3
2011 2
2012 4
2013 5
2014 5
2015 2
2016 8
2017 5
2018 9
2019 4
2020 5
2021 11
2022 5
2023 5
2024 3

Text availability

Article attribute

Article type

Publication date

Search Results

93 results

Results by year

Filters applied: . Clear all
Page 1
Design, synthesis, and biological evaluation of first-in-class indomethacin-based PROTACs degrading SARS-CoV-2 main protease and with broad-spectrum antiviral activity.
Desantis J, Bazzacco A, Eleuteri M, Tuci S, Bianconi E, Macchiarulo A, Mercorelli B, Loregian A, Goracci L. Desantis J, et al. Among authors: loregian a. Eur J Med Chem. 2024 Mar 15;268:116202. doi: 10.1016/j.ejmech.2024.116202. Epub 2024 Feb 6. Eur J Med Chem. 2024. PMID: 38394929 Free article.
Human neural progenitor cell models to study the antiviral effects and neuroprotective potential of approved and investigational human cytomegalovirus inhibitors.
Trevisan M, Pianezzola A, Onorati M, Apolloni L, Pistello M, Arav-Boger R, Palù G, Mercorelli B, Loregian A. Trevisan M, et al. Among authors: loregian a. Antiviral Res. 2024 Mar;223:105816. doi: 10.1016/j.antiviral.2024.105816. Epub 2024 Jan 28. Antiviral Res. 2024. PMID: 38286212 Free article.
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines.
Pacetti M, Pismataro MC, Felicetti T, Giammarino F, Bonomini A, Tiecco M, Bertagnin C, Barreca ML, Germani R, Cecchetti V, Vicenti I, Tabarrini O, Zazzi M, Loregian A, Massari S. Pacetti M, et al. Among authors: loregian a. Org Biomol Chem. 2024 Jan 24;22(4):767-783. doi: 10.1039/d3ob01861j. Org Biomol Chem. 2024. PMID: 38167738
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability.
Gao S, Song L, Sylvester K, Mercorelli B, Loregian A, Toth K, Weiße RH, Useini A, Sträter N, Yang M, Ye B, Tollefson AE, Müller CE, Liu X, Zhan P. Gao S, et al. Among authors: loregian a. J Med Chem. 2023 Dec 14;66(23):16426-16440. doi: 10.1021/acs.jmedchem.3c01876. Epub 2023 Nov 22. J Med Chem. 2023. PMID: 37992202
A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation.
Zhang J, Liu C, Jia R, Zhang X, Zhang J, Bertagnin C, Bonomini A, Guizzo L, Jiang Y, Jia H, Jia S, Ma X, Loregian A, Huang B, Zhan P, Liu X. Zhang J, et al. Among authors: loregian a. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2277135. doi: 10.1080/14756366.2023.2277135. Epub 2023 Nov 13. J Enzyme Inhib Med Chem. 2023. PMID: 37955306 Free PMC article.
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties.
Jia R, Zhang J, Shi F, Bonomini A, Lucca C, Bertagnin C, Zhang J, Liu C, Jia H, Jiang Y, Ma X, Loregian A, Huang B, Zhan P, Liu X. Jia R, et al. Among authors: loregian a. Eur J Med Chem. 2023 Apr 5;252:115275. doi: 10.1016/j.ejmech.2023.115275. Epub 2023 Mar 13. Eur J Med Chem. 2023. PMID: 36931117
Iterative Optimization and Structure-Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors via Targeting 150-Cavity.
Ju H, Hou L, Zhao F, Zhang Y, Jia R, Guizzo L, Bonomini A, Zhang J, Gao Z, Liang R, Bertagnin C, Kong X, Ma X, Kang D, Loregian A, Huang B, Liu X, Zhan P. Ju H, et al. Among authors: loregian a. J Med Chem. 2022 Sep 8;65(17):11550-11573. doi: 10.1021/acs.jmedchem.1c01970. Epub 2022 Aug 8. J Med Chem. 2022. PMID: 35939763
93 results