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Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies.
Azad T, Rezaei R, Singaravelu R, Pelin A, Boulton S, Petryk J, Onsu KA, Martin NT, Hoskin V, Ghahremani M, Marotel M, Marius R, He X, Crupi MJF, Hoang HD, Nik-Akhtar A, Ahmadi M, Zamani NK, Golshani A, Alain T, Greer P, Ardolino M, Dickinson BC, Tai LH, Ilkow CS, Bell JC. Azad T, et al. Among authors: ardolino m. Nat Commun. 2023 May 26;14(1):3035. doi: 10.1038/s41467-023-38651-x. Nat Commun. 2023. PMID: 37236967 Free PMC article.
Cytokine therapy reverses NK cell anergy in MHC-deficient tumors.
Ardolino M, Azimi CS, Iannello A, Trevino TN, Horan L, Zhang L, Deng W, Ring AM, Fischer S, Garcia KC, Raulet DH. Ardolino M, et al. J Clin Invest. 2014 Nov;124(11):4781-94. doi: 10.1172/JCI74337. Epub 2014 Oct 20. J Clin Invest. 2014. PMID: 25329698 Free PMC article.
Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells.
Spiegel A, Brooks MW, Houshyar S, Reinhardt F, Ardolino M, Fessler E, Chen MB, Krall JA, DeCock J, Zervantonakis IK, Iannello A, Iwamoto Y, Cortez-Retamozo V, Kamm RD, Pittet MJ, Raulet DH, Weinberg RA. Spiegel A, et al. Among authors: ardolino m. Cancer Discov. 2016 Jun;6(6):630-49. doi: 10.1158/2159-8290.CD-15-1157. Epub 2016 Apr 12. Cancer Discov. 2016. PMID: 27072748 Free PMC article.
The two-faces of NK cells in oncolytic virotherapy.
Marotel M, Hasim MS, Hagerman A, Ardolino M. Marotel M, et al. Among authors: ardolino m. Cytokine Growth Factor Rev. 2020 Dec;56:59-68. doi: 10.1016/j.cytogfr.2020.06.005. Epub 2020 Jun 13. Cytokine Growth Factor Rev. 2020. PMID: 32586674 Review.
CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness.
Abou-Hamad J, Hodgins JJ, de Souza CT, Garland B, Labrèche C, Marotel M, Gibson C, Delisle S, Pascoal J, Auer RC, Ardolino M, Sabourin LA. Abou-Hamad J, et al. Among authors: ardolino m. iScience. 2022 Nov 7;25(12):105524. doi: 10.1016/j.isci.2022.105524. eCollection 2022 Dec 22. iScience. 2022. PMID: 36437876 Free PMC article.
Targeting CD73 with flavonoids inhibits cancer stem cells and increases lymphocyte infiltration in a triple-negative breast cancer mouse model.
Mediratta K, El-Sahli S, Marotel M, Awan MZ, Kirkby M, Salkini A, Kurdieh R, Abdisalam S, Shrestha A, Di Censo C, Sulaiman A, McGarry S, Lavoie JR, Liu Z, Lee SH, Li X, Sciumè G, D'Costa VM, Ardolino M, Wang L. Mediratta K, et al. Among authors: ardolino m. Front Immunol. 2024 Mar 27;15:1366197. doi: 10.3389/fimmu.2024.1366197. eCollection 2024. Front Immunol. 2024. PMID: 38601156 Free PMC article.
Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade.
Hsu J, Hodgins JJ, Marathe M, Nicolai CJ, Bourgeois-Daigneault MC, Trevino TN, Azimi CS, Scheer AK, Randolph HE, Thompson TW, Zhang L, Iannello A, Mathur N, Jardine KE, Kirn GA, Bell JC, McBurney MW, Raulet DH, Ardolino M. Hsu J, et al. Among authors: ardolino m. J Clin Invest. 2018 Oct 1;128(10):4654-4668. doi: 10.1172/JCI99317. Epub 2018 Sep 10. J Clin Invest. 2018. PMID: 30198904 Free PMC article.
Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver.
Di Censo C, Marotel M, Mattiola I, Müller L, Scarno G, Pietropaolo G, Peruzzi G, Laffranchi M, Mazej J, Hasim MS, Asif S, Russo E, Tomaipitinca L, Stabile H, Lee SH, Vian L, Gadina M, Gismondi A, Shih HY, Mikami Y, Capuano C, Bernardini G, Bonelli M, Sozzani S, Diefenbach A, Ardolino M, Santoni A, Sciumè G. Di Censo C, et al. Among authors: ardolino m. Eur J Immunol. 2021 Nov;51(11):2568-2575. doi: 10.1002/eji.202149209. Epub 2021 Aug 19. Eur J Immunol. 2021. PMID: 34347289 Free PMC article.
47 results