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Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways.
Turcotte C, Dumais É, Archambault AS, Martin C, Blanchet MR, Bissonnette É, Boulet LP, Laviolette M, Di Marzo V, Flamand N. Turcotte C, et al. Among authors: archambault as. J Leukoc Biol. 2019 Dec;106(6):1337-1347. doi: 10.1002/JLB.3A0919-049RRR. Epub 2019 Sep 26. J Leukoc Biol. 2019. PMID: 31556464
Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoyl-glycerol and its congeners in human myeloid leukocytes.
Turcotte C, Archambault AS, Dumais É, Martin C, Blanchet MR, Bissonnette E, Ohashi N, Yamamoto K, Itoh T, Laviolette M, Veilleux A, Boulet LP, Di Marzo V, Flamand N. Turcotte C, et al. Among authors: archambault as. FASEB J. 2020 Mar;34(3):4253-4265. doi: 10.1096/fj.201902916R. Epub 2020 Feb 3. FASEB J. 2020. PMID: 32012340
Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in the skin and saliva.
Tinto F, Archambault AS, Dumais É, Rakotoarivelo V, Kostrzewa M, Martin C, Plante PL, Desjardins Y, Simard M, Pouliot R, De Petrocellis L, Ligresti A, Di Marzo V, Flamand N. Tinto F, et al. Among authors: archambault as. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Aug;1866(8):158954. doi: 10.1016/j.bbalip.2021.158954. Epub 2021 Apr 27. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 33915294
High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients.
Archambault AS, Zaid Y, Rakotoarivelo V, Turcotte C, Doré É, Dubuc I, Martin C, Flamand O, Amar Y, Cheikh A, Fares H, El Hassani A, Tijani Y, Côté A, Laviolette M, Boilard É, Flamand L, Flamand N. Archambault AS, et al. FASEB J. 2021 Jun;35(6):e21666. doi: 10.1096/fj.202100540R. FASEB J. 2021. PMID: 34033145 Free PMC article. Clinical Trial.
33 results