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9,10-Dihydr-oxy-4,4-dimethyl-5,8-dihydro-anthracen-1(4H)-one.
Ramírez-Rodríguez O, Martínez-Cifuentes M, Ibañez A, Vega A, Araya-Maturana R. Ramírez-Rodríguez O, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Jun 21;64(Pt 7):o1316. doi: 10.1107/S1600536808010891. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21202942 Free PMC article.
4-Acetyl-3,3-diethyl-5-hydr-oxy-2-morpholino-2,3-dihydro-1-benzofuran.
Vega A, Ramírez-Rodríguez O, Martínez-Cifuentes M, Ibañez A, Araya-Maturana R. Vega A, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 13;64(Pt 12):o2329. doi: 10.1107/S1600536808034065. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21581304 Free PMC article.
8,8-Diethyl-1,4,5,8-tetra-hydro-naphthalene-1,4,5-trione.
Vega A, Ramirez-Rodríguez O, Martínez-Cifuentes M, Ibañez A, Araya-Maturana R. Vega A, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Jan 17;65(Pt 2):o345. doi: 10.1107/S1600536809001755. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21581946 Free PMC article.
An ortho-carbonyl substituted hydroquinone derivative is an anticancer agent that acts by inhibiting mitochondrial bioenergetics and by inducing G₂/M-phase arrest in mammary adenocarcinoma TA3.
Urra FA, Martínez-Cifuentes M, Pavani M, Lapier M, Jaña-Prado F, Parra E, Maya JD, Pessoa-Mahana H, Ferreira J, Araya-Maturana R. Urra FA, et al. Toxicol Appl Pharmacol. 2013 Mar 15;267(3):218-27. doi: 10.1016/j.taap.2012.12.023. Epub 2013 Jan 17. Toxicol Appl Pharmacol. 2013. PMID: 23333614
Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation.
Urra FA, Córdova-Delgado M, Lapier M, Orellana-Manzano A, Acevedo-Arévalo L, Pessoa-Mahana H, González-Vivanco JM, Martínez-Cifuentes M, Ramírez-Rodríguez O, Millas-Vargas JP, Weiss-López B, Pavani M, Ferreira J, Araya-Maturana R. Urra FA, et al. Toxicol Appl Pharmacol. 2016 Jan 15;291:46-57. doi: 10.1016/j.taap.2015.12.005. Epub 2015 Dec 19. Toxicol Appl Pharmacol. 2016. PMID: 26712467
69 results