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From nature to market: examples of natural products that became drugs.
de Fátima A, Terra BS, da Silva CM, da Silva DL, Araujo DP, da Silva Neto L, Nascimento de Aquino RA. de Fátima A, et al. Among authors: araujo dp. Recent Pat Biotechnol. 2014;8(1):76-88. doi: 10.2174/1872208307666131220163108. Recent Pat Biotechnol. 2014. PMID: 24354526 Review.
2-Phthalimidethanol and 2-phthalimidethyl nitrate inhibit mechanical allodynia, neutrophil recruitment and cytokine and chemokine production in a murine model of articular inflammation.
Godin AM, Araújo DP, Menezes RR, de Brito AMS, Melo ISF, Coura GME, Bastos LFS, Amaral FA, Teixeira MM, de Fátima Â, Coelho MM, Machado RR. Godin AM, et al. Among authors: araujo dp. Pharmacol Rep. 2017 Aug;69(4):691-695. doi: 10.1016/j.pharep.2017.01.033. Epub 2017 Feb 8. Pharmacol Rep. 2017. PMID: 28550800
Activity of nicorandil, a nicotinamide derivative with a nitrate group, in the experimental model of pain induced by formaldehyde in mice.
Dutra MM, Godin AM, César IC, Nascimento EB Jr, Menezes RR, Ferreira WC, Soares DG, Seniuk JG, Araújo DP, Bastos LF, Pianetti GA, de Fátima Â, Machado RR, Coelho MM. Dutra MM, et al. Among authors: araujo dp. Pharmacol Biochem Behav. 2013 May;106:85-90. doi: 10.1016/j.pbb.2013.03.004. Epub 2013 Mar 26. Pharmacol Biochem Behav. 2013. PMID: 23537730 Free article.
Activities of 2-phthalimidethyl nitrate and 2-phthalimidethanol in the models of nociceptive response and edema induced by formaldehyde in mice and preliminary investigation of the underlying mechanisms.
Godin AM, Araújo DP, César IC, Menezes RR, Brito AM, Melo IS, Coura GM, Bastos LF, Almeida MO, Byrro RM, Matsui TC, Batista CR, Pianetti GA, de Fátima Â, Machado RR, Coelho MM. Godin AM, et al. Among authors: araujo dp. Eur J Pharmacol. 2015 Jun 5;756:59-66. doi: 10.1016/j.ejphar.2015.02.052. Epub 2015 Mar 17. Eur J Pharmacol. 2015. PMID: 25794846
Activities of 2-phthalimidethanol and 2-phthalimidethyl nitrate, phthalimide analogs devoid of the glutarimide moiety, in experimental models of inflammatory pain and edema.
Godin AM, Araújo DP, Menezes RR, Brito AM, Melo IS, Coura GM, Soares DG, Bastos LF, Amaral FA, Ribeiro LS, Boff D, Santos JR, Santos DA, Teixeira MM, de Fátima Â, Machado RR, Coelho MM. Godin AM, et al. Among authors: araujo dp. Pharmacol Biochem Behav. 2014 Jul;122:291-8. doi: 10.1016/j.pbb.2014.04.008. Epub 2014 Apr 26. Pharmacol Biochem Behav. 2014. PMID: 24780502
48 results