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Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis.
Mocci G, Sukhavasi K, Örd T, Bankier S, Singha P, Arasu UT, Agbabiaje OO, Mäkinen P, Ma L, Hodonsky CJ, Aherrahrou R, Muhl L, Liu J, Gustafsson S, Byandelger B, Wang Y, Koplev S, Lendahl U, Owens G, Leeper NJ, Pasterkamp G, Vanlandewijck M, Michoel T, Ruusalepp A, Hao K, Ylä-Herttuala S, Väli M, Järve H, Mokry M, Civelek M, Miller C, Kovacic JC, Kaikkonen MU, Betsholtz C, Björkegren JLM. Mocci G, et al. Among authors: arasu ut. Circ Res. 2024 Apr 19. doi: 10.1161/CIRCRESAHA.123.323184. Online ahead of print. Circ Res. 2024. PMID: 38639096 Free article.
Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells.
Deen AJ, Adinolfi S, Härkönen J, Patinen T, Liu X, Laitinen T, Takabe P, Kainulainen K, Pasonen-Seppänen S, Gawriyski LM, Arasu UT, Selvarajan I, Mäkinen P, Laitinen H, Kansanen E, Kaikkonen MU, Poso A, Varjosalo M, Levonen AL. Deen AJ, et al. Among authors: arasu ut. Redox Biol. 2024 Feb;69:103031. doi: 10.1016/j.redox.2024.103031. Epub 2024 Jan 4. Redox Biol. 2024. PMID: 38184997 Free PMC article.
Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease.
Darci-Maher N, Alvarez M, Arasu UT, Selvarajan I, Lee SHT, Pan DZ, Miao Z, Das SS, Kaminska D, Örd T, Benhammou JN, Wabitsch M, Pisegna JR, Männistö V, Pietiläinen KH, Laakso M, Sinsheimer JS, Kaikkonen MU, Pihlajamäki J, Pajukanta P. Darci-Maher N, et al. Among authors: arasu ut. EBioMedicine. 2023 Jun;92:104620. doi: 10.1016/j.ebiom.2023.104620. Epub 2023 May 22. EBioMedicine. 2023. PMID: 37224770 Free PMC article.
HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells.
Arasu UT, Deen AJ, Pasonen-Seppänen S, Heikkinen S, Lalowski M, Kärnä R, Härkönen K, Mäkinen P, Lázaro-Ibáñez E, Siljander PR, Oikari S, Levonen AL, Rilla K. Arasu UT, et al. Cell Mol Life Sci. 2020 Oct;77(20):4093-4115. doi: 10.1007/s00018-019-03399-5. Epub 2019 Dec 9. Cell Mol Life Sci. 2020. PMID: 31820036 Free PMC article.
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