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611 results

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Page 1
Simvastatin in Critically Ill Patients with Covid-19.
REMAP-CAP Investigators; Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF. REMAP-CAP Investigators, et al. Among authors: arabi y. N Engl J Med. 2023 Dec 21;389(25):2341-2354. doi: 10.1056/NEJMoa2309995. Epub 2023 Oct 25. N Engl J Med. 2023. PMID: 37888913 Free PMC article. Clinical Trial.
Failure of anticoagulant thromboprophylaxis: risk factors in medical-surgical critically ill patients*.
Lim W, Meade M, Lauzier F, Zarychanski R, Mehta S, Lamontagne F, Dodek P, McIntyre L, Hall R, Heels-Ansdell D, Fowler R, Pai M, Guyatt G, Crowther MA, Warkentin TE, Devereaux PJ, Walter SD, Muscedere J, Herridge M, Turgeon AF, Geerts W, Finfer S, Jacka M, Berwanger O, Ostermann M, Qushmaq I, Friedrich JO, Cook DJ; PROphylaxis for ThromboEmbolism in Critical Care Trial Investigators. Lim W, et al. Crit Care Med. 2015 Feb;43(2):401-10. doi: 10.1097/CCM.0000000000000713. Crit Care Med. 2015. PMID: 25474533 Clinical Trial.
Systematized and efficient: organization of critical care in the future.
Esper AM, Arabi YM, Cecconi M, Du B, Giamarellos-Bourboulis EJ, Juffermans N, Machado F, Peake S, Phua J, Rowan K, Suh GY, Martin GS. Esper AM, et al. Crit Care. 2022 Nov 28;26(1):366. doi: 10.1186/s13054-022-04244-1. Crit Care. 2022. PMID: 36443764 Free PMC article. Review.
Tocilizumab Outcomes in Critically Ill COVID-19 Patients Admitted to the ICU and the Role of Non-Tocilizumab COVID-19-Specific Medical Therapeutics.
Elhazmi A, Rabie AA, Al-Omari A, Mufti HN, Sallam H, Alshahrani MS, Mady A, Alghamdi A, Altalaq A, Azzam MH, Sindi A, Kharaba A, Al-Aseri ZA, Almekhlafi GA, Tashkandi W, Alajmi SA, Faqihi F, Alharthy A, Al-Tawfiq JA, Melibari RG, Arabi YM. Elhazmi A, et al. J Clin Med. 2023 Mar 16;12(6):2301. doi: 10.3390/jcm12062301. J Clin Med. 2023. PMID: 36983304 Free PMC article.
Proton pump inhibitors in critically ill mechanically ventilated patients with COVID-19: protocol for a substudy of the Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial.
Dennis BB, Thabane L, Heels-Ansdell D, Dionne JC, Binnie A, Tsang J, Guyatt G, Ahmed A, Lauzier F, Deane A, Arabi Y, Marshall J, Zytaruk N, Saunders L, Finfer S, Myburgh J, Muscedere J, English S, Ostermann M, Hardie M, Knowles S, Cook D; REVISE Investigators the Canadian Critical Care Trials Group. Dennis BB, et al. Among authors: arabi y. Trials. 2023 Aug 30;24(1):561. doi: 10.1186/s13063-023-07589-2. Trials. 2023. PMID: 37644556 Free PMC article.
Protocol and statistical analysis plan for the mega randomised registry trial comparing conservative vs. liberal oxygenation targets in adults with sepsis in the intensive care unit (Mega-ROX Sepsis).
Young PJ, Al-Fares A, Aryal D, Arabi YM, Ashraf MS, Bagshaw SM, Beane A, de Oliveira Manoel AL, Dullawe L, Fazla F, Fujii T, Haniffa R, Hodgson CL, Hunt A, Tirupakuzhi Vijayaraghavan BK, Landoni G, Lawrence C, Maia IS, Mackle D, Mazlan MZ, Nichol AD, Olatunji S, Rashan A, Rashan S, Kasza J; Mega-ROX management committee; Australian and New Zealand Intensive Care Society Clinical Trials Group; Critical Care Asia and Africa Network; Irish Critical Care-Clinical Trials Group. Young PJ, et al. Crit Care Resusc. 2023 May 22;25(2):106-112. doi: 10.1016/j.ccrj.2023.04.008. eCollection 2023 Jun. Crit Care Resusc. 2023. PMID: 37876605 Free PMC article.
Protocol and statistical analysis plan for the mega randomised registry trial comparing conservative vs. liberal oxygenation targets in adults with nonhypoxic ischaemic acute brain injuries and conditions in the intensive care unit (Mega-ROX Brains).
Young PJ, Al-Fares A, Aryal D, Arabi YM, Ashraf MS, Bagshaw SM, Mat-Nor MB, Beane A, Borghi G, de Oliveira Manoel AL, Dullawe L, Fazla F, Fujii T, Haniffa R, Hodgson CL, Hunt A, Lawrence C, Mackle D, Mangal K, Nichol AD, Olatunji S, Rashan A, Rashan S, Tomazini B, Kasza J; Mega-ROX management committee; Australian and New Zealand Intensive Care Society Clinical Trials Group; Brazilian Research in Intensive Care Network; Critical Care Asia and Africa Network; Irish Critical Care-Clinical Trials Group. Young PJ, et al. Crit Care Resusc. 2023 May 20;25(1):53-59. doi: 10.1016/j.ccrj.2023.04.011. eCollection 2023 Mar. Crit Care Resusc. 2023. PMID: 37876994 Free PMC article.
Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators; Adhikari NKJ, Hashmi M, Tirupakuzhi Vijayaraghavan BK, Haniffa R, Beane A, Webb SA, Angus DC, Gordon AC, Cook DJ, Guyatt GH, Berry LR, Lorenzi E, Mouncey PR, Au C, Pinto R, Ménard J, Sprague S, Masse MH, Huang DT, Heyland DK, Nichol AD, McArthur CJ, de Man A, Al-Beidh F, Annane D, Anstey M, Arabi YM, Battista MC, Berry S, Bhimani Z, Bonten MJM, Bradbury CA, Brant EB, Brunkhorst FM, Burrell A, Buxton M, Cecconi M, Cheng AC, Cohen D, Cove ME, Day AG, Derde LPG, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Goossens H, Green C, Higgins AM, Hills TE, Ichihara N, Jayakumar D, Kanji S, Khoso MN, Lawler PR, Lewis RJ, Litton E, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McQuilten ZK, McVerry BJ, Murthy S, Parke RL, Parker JC, Reyes LF, Rowan KM, Saito H, Salahuddin N, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Tolppa T, Trapani T, Turgeon AF, Turner AM, Udy AA, van de Veerdonk FL, Zarychanski R, Lamontagne F. LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators, et al. JAMA. 2023 Nov 14;330(18):1745-1759. doi: 10.1001/jama.2023.21407. JAMA. 2023. PMID: 37877585 Free PMC article.
Implementation of Recommendations on the Use of Corticosteroids in Severe COVID-19.
Camirand-Lemyre F, Merson L, Tirupakuzhi Vijayaraghavan BK, Burrell AJC, Citarella BW, Domingue MP, Lévesque S, Usuf E, Wils EJ, Ohshimo S, Martin-Loeches I, Sandulescu O, Laake JH, Lamontagne F; ISARIC Clinical Characterisation Group. Camirand-Lemyre F, et al. JAMA Netw Open. 2023 Dec 1;6(12):e2346502. doi: 10.1001/jamanetworkopen.2023.46502. JAMA Netw Open. 2023. PMID: 38147336 Free PMC article.
Patient-Level Meta-Analysis of Low-Dose Hydrocortisone in Adults with Septic Shock.
Pirracchio R, Annane D, Waschka AK, Lamontagne F, Arabi YM, Bollaert PE, Billot L, Du B, Briegel J, Cohen J, Finfer S, Gordon A, Hammond N, Hyvernat H, Keh D, Li Y, Liu L, Meduri GU, Mirea L, Myburgh JA, Sprung CL, Tilouche N, Tongyoo S, Venkatesh B, Zheng R, Delaney A. Pirracchio R, et al. Among authors: arabi ym. NEJM Evid. 2023 Jun;2(6):EVIDoa2300034. doi: 10.1056/EVIDoa2300034. Epub 2023 May 22. NEJM Evid. 2023. PMID: 38320130
611 results