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Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice.
Ramos da Silva J, Bitencourt Rodrigues K, Formoso Pelegrin G, Silva Sales N, Muramatsu H, de Oliveira Silva M, Porchia BFMM, Moreno ACR, Aps LRMM, Venceslau-Carvalho AA, Tombácz I, Fotoran WL, Karikó K, Lin PJC, Tam YK, de Oliveira Diniz M, Pardi N, de Souza Ferreira LC. Ramos da Silva J, et al. Among authors: aps lrmm. Sci Transl Med. 2023 Mar 8;15(686):eabn3464. doi: 10.1126/scitranslmed.abn3464. Epub 2023 Mar 8. Sci Transl Med. 2023. PMID: 36867683
Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites.
Porchia BFMM, Aps LRMM, Moreno ACR, da Silva JR, Silva MO, Sales NS, Alves RPDS, Rocha CRR, Silva MM, Rodrigues KB, Barros TB, Pagni RL, Souza PDC, Diniz MO, Ferreira LCS. Porchia BFMM, et al. Among authors: aps lrmm. Int J Biol Sci. 2022 Jan 1;18(1):15-29. doi: 10.7150/ijbs.56644. eCollection 2022. Int J Biol Sci. 2022. PMID: 34975315 Free PMC article.
A therapeutic DNA vaccine and gemcitabine act synergistically to eradicate HPV-associated tumors in a preclinical model.
Ramos da Silva J, Ramos Moreno AC, Silva Sales N, de Oliveira Silva M, Aps LRMM, Porchia BFMM, Bitencourt Rodrigues K, Cestari Moreno N, Venceslau-Carvalho AA, Menck CFM, de Oliveira Diniz M, de Souza Ferreira LC. Ramos da Silva J, et al. Among authors: aps lrmm. Oncoimmunology. 2021 Jul 25;10(1):1949896. doi: 10.1080/2162402X.2021.1949896. eCollection 2021. Oncoimmunology. 2021. PMID: 34367730 Free PMC article.
Antigen Delivery to DEC205+ Dendritic Cells Induces Immunological Memory and Protective Therapeutic Effects against HPV-Associated Tumors at Different Anatomical Sites.
Silva MO, Almeida BS, Sales NS, Diniz MO, Aps LRMM, Rodrigues KB, Silva JR, Moreno ACR, Porchia BFMM, Sulczewski FB, Boscardin SB, Ferreira LCS. Silva MO, et al. Among authors: aps lrmm. Int J Biol Sci. 2021 Jul 13;17(11):2944-2956. doi: 10.7150/ijbs.57038. eCollection 2021. Int J Biol Sci. 2021. PMID: 34345218 Free PMC article.
The Combined Use of Melatonin and an Indoleamine 2,3-Dioxygenase-1 Inhibitor Enhances Vaccine-Induced Protective Cellular Immunity to HPV16-Associated Tumors.
Moreno ACR, Porchia BFMM, Pagni RL, Souza PDC, Pegoraro R, Rodrigues KB, Barros TB, Aps LRMM, de Araújo EF, Calich VLG, Ferreira LCS. Moreno ACR, et al. Among authors: aps lrmm. Front Immunol. 2018 Aug 22;9:1914. doi: 10.3389/fimmu.2018.01914. eCollection 2018. Front Immunol. 2018. PMID: 30186285 Free PMC article.
14 results