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Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity.
Grandl G, Collden G, Feng J, Bhattacharya S, Klingelhuber F, Schomann L, Bilekova S, Ansarullah, Xu W, Far FF, Tost M, Gruber T, Bastidas-Ponce A, Zhang Q, Novikoff A, Liskiewicz A, Liskiewicz D, Garcia-Caceres C, Feuchtinger A, Tschöp MH, Krahmer N, Lickert H, Müller TD. Grandl G, et al. Nat Metab. 2024 Mar;6(3):448-457. doi: 10.1038/s42255-024-00991-3. Epub 2024 Feb 28. Nat Metab. 2024. PMID: 38418586 Free PMC article.
Targeting pancreatic β cells for diabetes treatment.
Jain C, Ansarullah, Bilekova S, Lickert H. Jain C, et al. Nat Metab. 2022 Sep;4(9):1097-1108. doi: 10.1038/s42255-022-00618-5. Epub 2022 Sep 21. Nat Metab. 2022. PMID: 36131204 Review.
Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes.
Oppenländer L, Palit S, Stemmer K, Greisle T, Sterr M, Salinno C, Bastidas-Ponce A, Feuchtinger A, Böttcher A, Ansarullah, Theis FJ, Lickert H. Oppenländer L, et al. Mol Metab. 2021 Dec;54:101330. doi: 10.1016/j.molmet.2021.101330. Epub 2021 Sep 6. Mol Metab. 2021. PMID: 34500108 Free PMC article.
Epithelial cell plasticity drives endoderm formation during gastrulation.
Scheibner K, Schirge S, Burtscher I, Büttner M, Sterr M, Yang D, Böttcher A, Ansarullah, Irmler M, Beckers J, Cernilogar FM, Schotta G, Theis FJ, Lickert H. Scheibner K, et al. Nat Cell Biol. 2021 Jul;23(7):692-703. doi: 10.1038/s41556-021-00694-x. Epub 2021 Jun 24. Nat Cell Biol. 2021. PMID: 34168324 Free PMC article.
New scavenger to fine-tune insulin action in β cells.
Hall C, Choi E. Hall C, et al. Cell Metab. 2021 Apr 6;33(4):707-708. doi: 10.1016/j.cmet.2021.03.013. Cell Metab. 2021. PMID: 33826914 Free article.
Insulin receptor signaling is crucial for beta cell homeostasis. In a recent issue of Nature, Ansarullah et al. (2021) have identified the insulin inhibitory receptor (inceptor), which balances insulin signaling by promoting insulin receptor internalization....
Insulin receptor signaling is crucial for beta cell homeostasis. In a recent issue of Nature, Ansarullah et al. (2021) have identifie …
Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia.
Ansarullah, Jain C, Far FF, Homberg S, Wißmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenländer L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Müller TD, Meier M, Tschöp MH, Coskun Ü, Lickert H. Ansarullah, et al. Nature. 2021 Apr;592(7852):E1. doi: 10.1038/s41586-021-03347-z. Nature. 2021. PMID: 33712809 No abstract available.
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