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Discovery of Cycloalkyl[c]thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2α Inhibitors.
J Med Chem. 2023 Jul 13;66(13):8666-8686. doi: 10.1021/acs.jmedchem.3c00332. Epub 2023 Jul 5.
J Med Chem. 2023.
PMID: 37403966
Discovery and Optimization of 2-Arylquinazolin-4-ones into a Potent and Selective Tankyrase Inhibitor Modulating Wnt Pathway Activity.
Buchstaller HP, Anlauf U, Dorsch D, Kuhn D, Lehmann M, Leuthner B, Musil D, Radtki D, Ritzert C, Rohdich F, Schneider R, Esdar C.
Buchstaller HP, et al. Among authors: anlauf u.
J Med Chem. 2019 Sep 12;62(17):7897-7909. doi: 10.1021/acs.jmedchem.9b00656. Epub 2019 Aug 20.
J Med Chem. 2019.
PMID: 31381853
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Optimization of a Screening Hit toward M2912, an Oral Tankyrase Inhibitor with Antitumor Activity in Colorectal Cancer Models.
Buchstaller HP, Anlauf U, Dorsch D, Kögler S, Kuhn D, Lehmann M, Leuthner B, Lodholz S, Musil D, Radtki D, Rettig C, Ritzert C, Rohdich F, Schneider R, Wegener A, Weigt S, Wilkinson K, Esdar C.
Buchstaller HP, et al. Among authors: anlauf u.
J Med Chem. 2021 Jul 22;64(14):10371-10392. doi: 10.1021/acs.jmedchem.1c00800. Epub 2021 Jul 13.
J Med Chem. 2021.
PMID: 34255518
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Parallel solution-phase synthesis of a 2-aminothiazole library including fully automated work-up.
Buchstaller HP, Anlauf U.
Buchstaller HP, et al. Among authors: anlauf u.
Comb Chem High Throughput Screen. 2011 Feb;14(2):104-8. doi: 10.2174/138620711794474024.
Comb Chem High Throughput Screen. 2011.
PMID: 21118081
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