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Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals.
Goikoetxea-Usandizaga N, Serrano-Maciá M, Delgado TC, Simón J, Fernández Ramos D, Barriales D, Cornide ME, Jiménez M, Pérez-Redondo M, Lachiondo-Ortega S, Rodríguez-Agudo R, Bizkarguenaga M, Zalamea JD, Pasco ST, Caballero-Díaz D, Alfano B, Bravo M, González-Recio I, Mercado-Gómez M, Gil-Pitarch C, Mabe J, Gracia-Sancho J, Abecia L, Lorenzo Ó, Martín-Sanz P, Abrescia NGA, Sabio G, Rincón M, Anguita J, Miñambres E, Martín C, Berenguer M, Fabregat I, Casado M, Peralta C, Varela-Rey M, Martínez-Chantar ML. Goikoetxea-Usandizaga N, et al. Among authors: anguita j. Hepatology. 2022 Mar;75(3):550-566. doi: 10.1002/hep.32149. Epub 2021 Dec 15. Hepatology. 2022. PMID: 34510498 Free PMC article.
MCJ/DnaJC15, an endogenous mitochondrial repressor of the respiratory chain that controls metabolic alterations.
Hatle KM, Gummadidala P, Navasa N, Bernardo E, Dodge J, Silverstrim B, Fortner K, Burg E, Suratt BT, Hammer J, Radermacher M, Taatjes DJ, Thornton T, Anguita J, Rincon M. Hatle KM, et al. Among authors: anguita j. Mol Cell Biol. 2013 Jun;33(11):2302-14. doi: 10.1128/MCB.00189-13. Epub 2013 Mar 25. Mol Cell Biol. 2013. PMID: 23530063 Free PMC article.
Regulation of oxidative stress by methylation-controlled J protein controls macrophage responses to inflammatory insults.
Navasa N, Martín I, Iglesias-Pedraz JM, Beraza N, Atondo E, Izadi H, Ayaz F, Fernández-Álvarez S, Hatle K, Som A, Dienz O, Osborne BA, Martínez-Chantar ML, Rincón M, Anguita J. Navasa N, et al. Among authors: anguita j. J Infect Dis. 2015 Jan 1;211(1):135-45. doi: 10.1093/infdis/jiu389. Epub 2014 Jul 14. J Infect Dis. 2015. PMID: 25028693 Free PMC article.
Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1.
Barbier-Torres L, Beraza N, Fernández-Tussy P, Lopitz-Otsoa F, Fernández-Ramos D, Zubiete-Franco I, Varela-Rey M, Delgado TC, Gutiérrez V, Anguita J, Pares A, Banales JM, Villa E, Caballería J, Alvarez L, Lu SC, Mato JM, Martínez-Chantar ML. Barbier-Torres L, et al. Among authors: anguita j. Hepatology. 2015 Oct;62(4):1237-48. doi: 10.1002/hep.27959. Epub 2015 Jul 31. Hepatology. 2015. PMID: 26109312 Free PMC article.
Ikaros mediates the DNA methylation-independent silencing of MCJ/DNAJC15 gene expression in macrophages.
Navasa N, Martin-Ruiz I, Atondo E, Sutherland JD, Angel Pascual-Itoiz M, Carreras-González A, Izadi H, Tomás-Cortázar J, Ayaz F, Martin-Martin N, Torres IM, Barrio R, Carracedo A, Olivera ER, Rincón M, Anguita J. Navasa N, et al. Among authors: anguita j. Sci Rep. 2015 Sep 30;5:14692. doi: 10.1038/srep14692. Sci Rep. 2015. PMID: 26419808 Free PMC article.
Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus.
Champagne DP, Hatle KM, Fortner KA, D'Alessandro A, Thornton TM, Yang R, Torralba D, Tomás-Cortázar J, Jun YW, Ahn KH, Hansen KC, Haynes L, Anguita J, Rincon M. Champagne DP, et al. Among authors: anguita j. Immunity. 2016 Jun 21;44(6):1299-311. doi: 10.1016/j.immuni.2016.02.018. Epub 2016 May 24. Immunity. 2016. PMID: 27234056 Free PMC article.
Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.
Alonso C, Fernández-Ramos D, Varela-Rey M, Martínez-Arranz I, Navasa N, Van Liempd SM, Lavín Trueba JL, Mayo R, Ilisso CP, de Juan VG, Iruarrizaga-Lejarreta M, delaCruz-Villar L, Mincholé I, Robinson A, Crespo J, Martín-Duce A, Romero-Gómez M, Sann H, Platon J, Van Eyk J, Aspichueta P, Noureddin M, Falcón-Pérez JM, Anguita J, Aransay AM, Martínez-Chantar ML, Lu SC, Mato JM. Alonso C, et al. Among authors: anguita j. Gastroenterology. 2017 May;152(6):1449-1461.e7. doi: 10.1053/j.gastro.2017.01.015. Epub 2017 Jan 26. Gastroenterology. 2017. PMID: 28132890 Free PMC article.
The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant.
Tomás-Cortázar J, Martín-Ruiz I, Barriales D, Pascual-Itoiz MÁ, de Juan VG, Caro-Maldonado A, Merino N, Marina A, Blanco FJ, Flores JM, Sutherland JD, Barrio R, Rojas A, Martínez-Chantar ML, Carracedo A, Simó C, García-Cañas V, Abecia L, Lavín JL, Aransay AM, Rodríguez H, Anguita J. Tomás-Cortázar J, et al. Among authors: anguita j. Sci Rep. 2017 Sep 6;7(1):10740. doi: 10.1038/s41598-017-11354-2. Sci Rep. 2017. PMID: 28878331 Free PMC article.
240 results