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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
Manry J, Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Mégarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs CM, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY, Shcherbina A, Lau… See abstract for full author list ➔ Manry J, et al. Among authors: anglicheau d. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2200413119. doi: 10.1073/pnas.2200413119. Epub 2022 May 16. Proc Natl Acad Sci U S A. 2022. PMID: 35576468 Free PMC article.
Temporal virus serological profiling of kidney graft recipients using VirScan.
Isnard P, Kula T, Avettand Fenoel V, Anglicheau D, Terzi F, Legendre C, Elledge SJ, Canaud G. Isnard P, et al. Among authors: anglicheau d. Proc Natl Acad Sci U S A. 2019 May 28;116(22):10899-10904. doi: 10.1073/pnas.1821166116. Epub 2019 May 13. Proc Natl Acad Sci U S A. 2019. PMID: 31085644 Free PMC article.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, K… See abstract for full author list ➔ Bastard P, et al. Among authors: anglicheau d. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
MicroRNAs in kidney injury and disease.
Mahtal N, Lenoir O, Tinel C, Anglicheau D, Tharaux PL. Mahtal N, et al. Among authors: anglicheau d. Nat Rev Nephrol. 2022 Oct;18(10):643-662. doi: 10.1038/s41581-022-00608-6. Epub 2022 Aug 16. Nat Rev Nephrol. 2022. PMID: 35974169 Review.
MicroRNA expression profiles predictive of human renal allograft status.
Anglicheau D, Sharma VK, Ding R, Hummel A, Snopkowski C, Dadhania D, Seshan SV, Suthanthiran M. Anglicheau D, et al. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5330-5. doi: 10.1073/pnas.0813121106. Epub 2009 Mar 16. Proc Natl Acad Sci U S A. 2009. PMID: 19289845 Free PMC article.
Late-onset post-transplantation lymphoproliferative disorders after kidney transplantation: a monocentric study over three decades.
Michonneau D, Suarez F, Lambert J, Adam J, Brousse N, Canioni D, Anglicheau D, Martinez F, Snanoudj R, Legendre C, Hermine O, Mamzer-Bruneel MF. Michonneau D, et al. Among authors: anglicheau d. Nephrol Dial Transplant. 2013 Feb;28(2):471-8. doi: 10.1093/ndt/gfs476. Epub 2012 Nov 4. Nephrol Dial Transplant. 2013. PMID: 23129824
A Novel Extrinsic Pathway for the Unfolded Protein Response in the Kidney.
Mami I, Tavernier Q, Bouvier N, Aboukamis R, Desbuissons G, Rabant M, Poindessous V, Laurent-Puig P, Beaune P, Tharaux PL, Thervet E, Chevet E, Anglicheau D, Pallet N. Mami I, et al. Among authors: anglicheau d. J Am Soc Nephrol. 2016 Sep;27(9):2670-83. doi: 10.1681/ASN.2015060703. Epub 2016 Jan 28. J Am Soc Nephrol. 2016. PMID: 26823555 Free PMC article.
An initial report from the French SOT COVID Registry suggests high mortality due to COVID-19 in recipients of kidney transplants.
Caillard S, Anglicheau D, Matignon M, Durrbach A, Greze C, Frimat L, Thaunat O, Legris T, Moal V, Westeel PF, Kamar N, Gatault P, Snanoudj R, Sicard A, Bertrand D, Colosio C, Couzi L, Chemouny JM, Masset C, Blancho G, Bamoulid J, Duveau A, Bouvier N, Chavarot N, Grimbert P, Moulin B, Le Meur Y, Hazzan M; French SOT COVID Registry. Caillard S, et al. Among authors: anglicheau d. Kidney Int. 2020 Dec;98(6):1549-1558. doi: 10.1016/j.kint.2020.08.005. Epub 2020 Aug 24. Kidney Int. 2020. PMID: 32853631 Free PMC article.
COVID-19 severity in kidney transplant recipients is similar to nontransplant patients with similar comorbidities.
Chavarot N, Gueguen J, Bonnet G, Jdidou M, Trimaille A, Burger C, Amrouche L, Weizman O, Pommier T, Aubert O, Celier J, Sberro-Soussan R, Geneste L, Panagides V, Delahousse M, Marsou W, Aguilar C, Deney A, Zuber J, Fauvel C, Legendre C, Mika D, Pezel T, Anglicheau D, Sutter W, Zaidan M, Snanoudj R, Cohen A, Scemla A; Critical COVID-19 France Investigators. Chavarot N, et al. Among authors: anglicheau d. Am J Transplant. 2021 Mar;21(3):1285-1294. doi: 10.1111/ajt.16416. Epub 2021 Jan 4. Am J Transplant. 2021. PMID: 33252201 Free PMC article.
Is COVID-19 infection more severe in kidney transplant recipients?
Caillard S, Chavarot N, Francois H, Matignon M, Greze C, Kamar N, Gatault P, Thaunat O, Legris T, Frimat L, Westeel PF, Goutaudier V, Jdidou M, Snanoudj R, Colosio C, Sicard A, Bertrand D, Mousson C, Bamoulid J, Masset C, Thierry A, Couzi L, Chemouny JM, Duveau A, Moal V, Blancho G, Grimbert P, Durrbach A, Moulin B, Anglicheau D, Ruch Y, Kaeuffer C, Benotmane I, Solis M, LeMeur Y, Hazzan M, Danion F; French SOT COVID Registry. Caillard S, et al. Among authors: anglicheau d. Am J Transplant. 2021 Mar;21(3):1295-1303. doi: 10.1111/ajt.16424. Epub 2021 Jan 28. Am J Transplant. 2021. PMID: 33259686 Free PMC article.
258 results