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Page 1
Strategies to design clinical studies to identify predictive biomarkers in cancer research.
Perez-Gracia JL, Sanmamed MF, Bosch A, Patiño-Garcia A, Schalper KA, Segura V, Bellmunt J, Tabernero J, Sweeney CJ, Choueiri TK, Martín M, Fusco JP, Rodriguez-Ruiz ME, Calvo A, Prior C, Paz-Ares L, Pio R, Gonzalez-Billalabeitia E, Gonzalez Hernandez A, Páez D, Piulats JM, Gurpide A, Andueza M, de Velasco G, Pazo R, Grande E, Nicolas P, Abad-Santos F, Garcia-Donas J, Castellano D, Pajares MJ, Suarez C, Colomer R, Montuenga LM, Melero I. Perez-Gracia JL, et al. Among authors: andueza m. Cancer Treat Rev. 2017 Feb;53:79-97. doi: 10.1016/j.ctrv.2016.12.005. Epub 2016 Dec 30. Cancer Treat Rev. 2017. PMID: 28088073 Free article. Review.
Identification of mutations associated with acquired resistance to sunitinib in renal cell cancer.
Elgendy M, Fusco JP, Segura V, Lozano MD, Minucci S, Echeveste JI, Gurpide A, Andueza M, Melero I, Sanmamed MF, Ruiz MR, Calvo A, Pascual JI, Velis JM, Miñana B, Valle RD, Pio R, Agorreta J, Abengozar M, Colecchia M, Brich S, Renne SL, Guruceaga E, Patiño-García A, Perez-Gracia JL. Elgendy M, et al. Among authors: andueza m. Int J Cancer. 2019 Oct 1;145(7):1991-2001. doi: 10.1002/ijc.32256. Epub 2019 Mar 30. Int J Cancer. 2019. PMID: 30848481 Free article.
Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarcinoma.
Patiño-García A, Guruceaga E, Andueza MP, Ocón M, Fodop Sokoudjou JJ, de Villalonga Zornoza N, Alkorta-Aranburu G, Uria IT, Gurpide A, Camps C, Jantus-Lewintre E, Navamuel-Andueza M, Sanmamed MF, Melero I, Elgendy M, Fusco JP, Zulueta JJ, de-Torres JP, Bastarrika G, Seijo L, Pio R, Montuenga LM, Hernáez M, Ochoa I, Perez-Gracia JL. Patiño-García A, et al. Among authors: andueza mp. EBioMedicine. 2024 Apr;102:105048. doi: 10.1016/j.ebiom.2024.105048. Epub 2024 Mar 13. EBioMedicine. 2024. PMID: 38484556 Free PMC article.
Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis.
Ortiz-Espinosa S, Morales X, Senent Y, Alignani D, Tavira B, Macaya I, Ruiz B, Moreno H, Remírez A, Sainz C, Rodriguez-Pena A, Oyarbide A, Ariz M, Andueza MP, Valencia K, Teijeira A, Hoehlig K, Vater A, Rolfe B, Woodruff TM, Lopez-Picazo JM, Vicent S, Kochan G, Escors D, Gil-Bazo I, Perez-Gracia JL, Montuenga LM, Lambris JD, Ortiz de Solorzano C, Lecanda F, Ajona D, Pio R. Ortiz-Espinosa S, et al. Among authors: andueza mp. Cancer Lett. 2022 Mar 31;529:70-84. doi: 10.1016/j.canlet.2021.12.027. Epub 2021 Dec 28. Cancer Lett. 2022. PMID: 34971753
Differential Interleukin-8 thresholds for chemotaxis and netosis in human neutrophils.
Teijeira A, Garasa S, Ochoa MDC, Cirella A, Olivera I, Glez-Vaz J, Andueza MP, Migueliz I, Alvarez M, Rodríguez-Ruiz ME, Rouzaut A, Berraondo P, Sanmamed MF, Perez Gracia JL, Melero I. Teijeira A, et al. Among authors: andueza mp. Eur J Immunol. 2021 Sep;51(9):2274-2280. doi: 10.1002/eji.202049029. Epub 2021 Jun 4. Eur J Immunol. 2021. PMID: 33963542 Free article.
Whole exome sequencing characterization of individuals presenting extreme phenotypes of high and low risk of developing tobacco-induced lung adenocarcinoma.
Patiño-García A, Guruceaga E, Segura V, Sánchez Bayona R, Andueza MP, Tamayo Uria I, Serrano G, Fusco JP, Pajares MJ, Gurpide A, Ocón M, Sanmamed MF, Rodriguez Ruiz M, Melero I, Lozano MD, de Andrea C, Pita G, Gonzalez-Neira A, Gonzalez A, Zulueta JJ, Montuenga LM, Pio R, Perez-Gracia JL. Patiño-García A, et al. Among authors: andueza mp. Transl Lung Cancer Res. 2021 Mar;10(3):1327-1337. doi: 10.21037/tlcr-20-1197. Transl Lung Cancer Res. 2021. PMID: 33889513 Free PMC article.
Characterization of the perioperative changes of exosomal immune-related cytokines induced by prostatectomy in early-stage prostate cancer patients.
Macías M, García-Cortés Á, Torres M, Ancizu-Marckert J, Ignacio Pascual J, Díez-Caballero F, Enrique Robles J, Rosell D, Miñana B, Mateos B, Ajona D, Sánchez-Bayona R, Bedialauneta O, Chocarro S, Navarro A, Andueza MP, Gúrpide A, Luis Perez-Gracia J, Alegre E, González Á. Macías M, et al. Among authors: andueza mp. Cytokine. 2021 May;141:155471. doi: 10.1016/j.cyto.2021.155471. Epub 2021 Feb 16. Cytokine. 2021. PMID: 33607398 Free article. Clinical Trial.
Performance comparison of two next-generation sequencing panels to detect actionable mutations in cell-free DNA in cancer patients.
Macías M, Cañada-Higueras E, Alegre E, Bielsa A, Gracia J, Patiño-García A, Ferrer-Costa R, Sendino T, Andueza MP, Mateos B, Rodríguez J, Corral J, Gúrpide A, Lopez-Picazo JM, Perez-Gracia JL, Gil-Bazo I, Alkorta-Aranburu G, González Á. Macías M, et al. Among authors: andueza mp. Clin Chem Lab Med. 2020 Jul 28;58(8):1341-1348. doi: 10.1515/cclm-2019-1267. Clin Chem Lab Med. 2020. PMID: 32623849
CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity.
Teijeira Á, Garasa S, Gato M, Alfaro C, Migueliz I, Cirella A, de Andrea C, Ochoa MC, Otano I, Etxeberria I, Andueza MP, Nieto CP, Resano L, Azpilikueta A, Allegretti M, de Pizzol M, Ponz-Sarvisé M, Rouzaut A, Sanmamed MF, Schalper K, Carleton M, Mellado M, Rodriguez-Ruiz ME, Berraondo P, Perez-Gracia JL, Melero I. Teijeira Á, et al. Among authors: andueza mp. Immunity. 2020 May 19;52(5):856-871.e8. doi: 10.1016/j.immuni.2020.03.001. Epub 2020 Apr 13. Immunity. 2020. PMID: 32289253 Free article.
The Dynamic Use of EGFR Mutation Analysis in Cell-Free DNA as a Follow-Up Biomarker during Different Treatment Lines in Non-Small-Cell Lung Cancer Patients.
Macías M, Alegre E, Alkorta-Aranburu G, Patiño-García A, Mateos B, Andueza MP, Gúrpide A, Lopez-Picazo JM, Gil-Bazo I, Perez-Gracia JL, González Á. Macías M, et al. Among authors: andueza mp. Dis Markers. 2019 Jan 23;2019:7954921. doi: 10.1155/2019/7954921. eCollection 2019. Dis Markers. 2019. PMID: 30809319 Free PMC article.
18 results