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Synthetic cyclopenta[b]indoles exhibit antineoplastic activity by targeting microtubule dynamics in acute myeloid leukemia cells.
Vicari HP, Lima K, Gomes RDC, Fernandes DC, da Silva JCL, Rodrigues Junior MT, Barroso de Oliveira AS, Dos Santos RN, Andricopulo AD, Coelho F, Costa-Lotufo LV, Machado-Neto JA. Vicari HP, et al. Among authors: andricopulo ad. Eur J Pharmacol. 2021 Mar 5;894:173853. doi: 10.1016/j.ejphar.2021.173853. Epub 2021 Jan 8. Eur J Pharmacol. 2021. PMID: 33422507
N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia.
Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira AB, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, de Souza Melo CP, Silveira AB, Leal PC, Frederico MJ, do Nascimento LF, Santos AR, Andricopulo AD, Day BW, Yunes RA, Vogt A, Yunes JA, Nunes RJ. Salum LB, et al. Among authors: andricopulo ad. Eur J Med Chem. 2015;96:504-18. doi: 10.1016/j.ejmech.2015.02.041. Epub 2015 Feb 23. Eur J Med Chem. 2015. PMID: 25951294
Molecular docking and structure-based drug design strategies.
Ferreira LG, Dos Santos RN, Oliva G, Andricopulo AD. Ferreira LG, et al. Among authors: andricopulo ad. Molecules. 2015 Jul 22;20(7):13384-421. doi: 10.3390/molecules200713384. Molecules. 2015. PMID: 26205061 Free PMC article. Review.
Endophytic Actinobacteria from the Brazilian Medicinal Plant Lychnophora ericoides Mart. and the Biological Potential of Their Secondary Metabolites.
Conti R, Chagas FO, Caraballo-Rodriguez AM, Melo WG, do Nascimento AM, Cavalcanti BC, de Moraes MO, Pessoa C, Costa-Lotufo LV, Krogh R, Andricopulo AD, Lopes NP, Pupo MT. Conti R, et al. Among authors: andricopulo ad. Chem Biodivers. 2016 Jun;13(6):727-36. doi: 10.1002/cbdv.201500225. Epub 2016 May 20. Chem Biodivers. 2016. PMID: 27128202
Diastereoselective Synthesis of Biologically Active Cyclopenta[b]indoles.
Santos MS, Fernandes DC, Rodrigues MT Jr, Regiani T, Andricopulo AD, Ruiz AL, Vendramini-Costa DB, de Carvalho JE, Eberlin MN, Coelho F. Santos MS, et al. Among authors: andricopulo ad. J Org Chem. 2016 Aug 5;81(15):6626-39. doi: 10.1021/acs.joc.6b01270. Epub 2016 Jul 28. J Org Chem. 2016. PMID: 27403650
160 results