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FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis.
Liu C, Schönke M, Spoorenberg B, Lambooij JM, van der Zande HJP, Zhou E, Tushuizen ME, Andreasson AC, Park A, Oldham S, Uhrbom M, Ahlstedt I, Ikeda Y, Wallenius K, Peng XR, Guigas B, Boon MR, Wang Y, Rensen PCN. Liu C, et al. Among authors: andreasson ac. Elife. 2023 Jan 17;12:e83075. doi: 10.7554/eLife.83075. Elife. 2023. PMID: 36648330 Free PMC article.
TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis.
Petkevicius K, Palmgren H, Glover MS, Ahnmark A, Andréasson AC, Madeyski-Bengtson K, Kawana H, Allman EL, Kaper D, Uhrbom M, Andersson L, Aasehaug L, Forsström J, Wallin S, Ahlstedt I, Leke R, Karlsson D, González-King H, Löfgren L, Nilsson R, Pellegrini G, Kono N, Aoki J, Hess S, Sienski G, Pilon M, Bohlooly-Y M, Maresca M, Peng XR. Petkevicius K, et al. Among authors: andreasson ac. Nat Commun. 2022 Oct 14;13(1):6020. doi: 10.1038/s41467-022-33735-6. Nat Commun. 2022. PMID: 36241646 Free PMC article.
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice.
Lindén D, Ahnmark A, Pingitore P, Ciociola E, Ahlstedt I, Andréasson AC, Sasidharan K, Madeyski-Bengtson K, Zurek M, Mancina RM, Lindblom A, Bjursell M, Böttcher G, Ståhlman M, Bohlooly-Y M, Haynes WG, Carlsson B, Graham M, Lee R, Murray S, Valenti L, Bhanot S, Åkerblad P, Romeo S. Lindén D, et al. Among authors: andreasson ac. Mol Metab. 2019 Apr;22:49-61. doi: 10.1016/j.molmet.2019.01.013. Epub 2019 Feb 5. Mol Metab. 2019. PMID: 30772256 Free PMC article.
Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.
Palmgren H, Petkevicius K, Bartesaghi S, Ahnmark A, Ruiz M, Nilsson R, Löfgren L, Glover MS, Andréasson AC, Andersson L, Becquart C, Kurczy M, Kull B, Wallin S, Karlsson D, Hess S, Maresca M, Bohlooly-Y M, Peng XR, Pilon M. Palmgren H, et al. Among authors: andreasson ac. Diabetes. 2023 Oct 1;72(10):1350-1363. doi: 10.2337/db22-0293. Diabetes. 2023. PMID: 36580483 Free PMC article.
Modeling human pancreatic beta cell dedifferentiation.
Diedisheim M, Oshima M, Albagli O, Huldt CW, Ahlstedt I, Clausen M, Menon S, Aivazidis A, Andreasson AC, Haynes WG, Marchetti P, Marselli L, Armanet M, Chimienti F, Scharfmann R. Diedisheim M, et al. Among authors: andreasson ac. Mol Metab. 2018 Apr;10:74-86. doi: 10.1016/j.molmet.2018.02.002. Epub 2018 Feb 8. Mol Metab. 2018. PMID: 29472102 Free PMC article.
Hepatic patatin-like phospholipase domain-containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans.
Ericson E, Bergenholm L, Andréasson AC, Dix CI, Knöchel J, Hansson SF, Lee R, Schumi J, Antonsson M, Fjellström O, Nasr P, Liljeblad M, Carlsson B, Kechagias S, Lindén D, Ekstedt M. Ericson E, et al. Among authors: andreasson ac. Hepatol Commun. 2022 Oct;6(10):2689-2701. doi: 10.1002/hep4.2032. Epub 2022 Jul 14. Hepatol Commun. 2022. PMID: 35833455 Free PMC article.
PCSK9 rs11591147 R46L loss-of-function variant protects against liver damage in individuals with NAFLD.
Grimaudo S, Bartesaghi S, Rametta R, Marra F, Margherita Mancina R, Pihlajamäki J, Kakol-Palm D, Andréasson AC, Dongiovanni P, Ludovica Fracanzani A, Lori G, Männistö V, Pellegrini G, Bohlooly-Y M, Pennisi G, Maria Pipitone R, Spagnuolo R, Craxì A, Lindén D, Valenti L, Romeo S, Petta S. Grimaudo S, et al. Among authors: andreasson ac. Liver Int. 2021 Feb;41(2):321-332. doi: 10.1111/liv.14711. Epub 2020 Nov 2. Liver Int. 2021. PMID: 33091218
The APOE∗3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis.
Pouwer MG, Heinonen SE, Behrendt M, Andréasson AC, van Koppen A, Menke AL, Pieterman EJ, van den Hoek AM, Jukema JW, Leighton B, Jönsson-Rylander AC, Princen HMG. Pouwer MG, et al. Among authors: andreasson ac. J Diabetes Res. 2019 Feb 21;2019:9727952. doi: 10.1155/2019/9727952. eCollection 2019. J Diabetes Res. 2019. PMID: 30949516 Free PMC article.
Hyperglycemia Induced by Glucokinase Deficiency Accelerates Atherosclerosis Development and Impairs Lesion Regression in Combined Heterozygous Glucokinase and the Apolipoprotein E-Knockout Mice.
Adingupu DD, Heinonen SE, Andréasson AC, Brusberg M, Ahnmark A, Behrendt M, Leighton B, Jönsson-Rylander AC. Adingupu DD, et al. Among authors: andreasson ac. J Diabetes Res. 2016;2016:8630961. doi: 10.1155/2016/8630961. Epub 2016 Sep 28. J Diabetes Res. 2016. PMID: 27774459 Free PMC article.
17 results