Evaluating cell culture reliability in pediatric brain tumor primary cells through DNA methylation profiling.
Pedace L, Pizzi S, Abballe L, Vinci M, Antonacci C, Patrizi S, Nardini C, Del Bufalo F, Rossi S, Pericoli G, Gianno F, Besharat ZM, Tiberi L, Mastronuzzi A, Ferretti E, Tartaglia M, Locatelli F, Ciolfi A, Miele E.
Pedace L, et al.
NPJ Precis Oncol. 2024 Apr 18;8(1):92. doi: 10.1038/s41698-024-00578-x.
NPJ Precis Oncol. 2024.
PMID: 38637626
Free PMC article.
We identified a set of hypomethylated genes shared among unfaithful cells converging on response to growth factors and migration pathways, such as signaling cascade activation, tissue organization, and cellular migration. In conclusion, DNAm and CNV are informative tools t …
We identified a set of hypomethylated genes shared among unfaithful cells converging on response to growth factors and migration pathways, s …