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2014 2
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2017 5
2018 3
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Page 1
Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice.
Schaftenaar FH, van Dam AD, de Bruin G, Depuydt MAC, Mol J, Amersfoort J, Douna H, Meijer M, Kröner MJ, van Santbrink PJ, Bernabé Kleijn MNA, van Puijvelde GHM, Florea BI, Slütter B, Foks AC, Bot I, Rensen PCN, Kuiper J. Schaftenaar FH, et al. Among authors: van dam ad. Arterioscler Thromb Vasc Biol. 2024 Apr 25. doi: 10.1161/ATVBAHA.123.319701. Online ahead of print. Arterioscler Thromb Vasc Biol. 2024. PMID: 38660806
OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity.
Purvis GSD, Collino M, van Dam AD, Einaudi G, Ng Y, Shanmuganathan M, Patel SY, Thiemermann C, Channon KM, Greaves DR; Oxford Acute Myocardial Infarction (OxAMI) Study. Purvis GSD, et al. Among authors: van dam ad. Diabetes. 2024 Jan 8:db220275. doi: 10.2337/db22-0275. Online ahead of print. Diabetes. 2024. PMID: 38193882
HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution.
Kuo FC, Neville MJ, Sabaratnam R, Wesolowska-Andersen A, Phillips D, Wittemans LBL, van Dam AD, Loh NY, Todorčević M, Denton N, Kentistou KA, Joshi PK, Christodoulides C, Langenberg C, Collas P, Karpe F, Pinnick KE. Kuo FC, et al. Among authors: van dam ad. Cell Rep. 2022 Jul 26;40(4):111136. doi: 10.1016/j.celrep.2022.111136. Cell Rep. 2022. PMID: 35905723 Free PMC article.
Higher Plasma Sclerostin and Lower Wnt Signaling Gene Expression in White Adipose Tissue of Prediabetic South Asian Men Compared with White Caucasian Men.
Janssen LGM, Van Dam AD, Hanssen MJW, Kooijman S, Nahon KJ, Reinders H, Jazet IM, Van Marken Lichtenbelt WD, Rensen PCN, Appelman-Dijkstra NM, Boon MR. Janssen LGM, et al. Among authors: van dam ad. Diabetes Metab J. 2020 Apr;44(2):326-335. doi: 10.4093/dmj.2019.0031. Epub 2019 Oct 31. Diabetes Metab J. 2020. PMID: 31701693 Free PMC article. Clinical Trial.
Conditionally immortalized brown preadipocytes can switch between proliferative and differentiated states.
Liu J, Kuipers EN, Sips HCM, Dorleijn JC, van Dam AD, Christodoulides C, Karpe F, Zhou G, Boon MR, Rensen PCN, de Vries AAF, Kooijman S. Liu J, et al. Among authors: van dam ad. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Dec;1864(12):158511. doi: 10.1016/j.bbalip.2019.08.007. Epub 2019 Aug 26. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31465889 Free article.
IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake.
Kuipers EN, van Dam AD, Ballak DB, de Wit EA, Dinarello CA, Stienstra R, van Diepen JA, Rensen PCN, Boon MR. Kuipers EN, et al. Among authors: van dam ad. Int J Mol Sci. 2018 Aug 2;19(8):2264. doi: 10.3390/ijms19082264. Int J Mol Sci. 2018. PMID: 30072596 Free PMC article.
The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.
Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M. Schilperoort M, et al. Among authors: van dam ad. EMBO Mol Med. 2018 Mar;10(3):e8047. doi: 10.15252/emmm.201708047. EMBO Mol Med. 2018. PMID: 29343498 Free PMC article.
Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis.
Hoeke G, Wang Y, van Dam AD, Mol IM, Gart E, Klop HG, van den Berg SM, Pieterman EH, Princen HMG, Groen AK, Rensen PCN, Berbée JFP, Boon MR. Hoeke G, et al. Among authors: van dam ad. Atherosclerosis. 2017 Dec;267:116-126. doi: 10.1016/j.atherosclerosis.2017.10.030. Epub 2017 Oct 26. Atherosclerosis. 2017. PMID: 29121499
22 results