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Immune biomarkers: how well do they serve prognosis in human cancers?
Baxevanis CN, Anastasopoulou EA, Voutsas IF, Papamichail M, Perez SA. Baxevanis CN, et al. Among authors: anastasopoulou ea. Expert Rev Mol Diagn. 2015 Jan;15(1):49-59. doi: 10.1586/14737159.2015.965684. Epub 2014 Oct 27. Expert Rev Mol Diagn. 2015. PMID: 25345403 Review.
A pilot study in prostate cancer patients treated with the AE37 Ii-key-HER-2/neu polypeptide vaccine suggests that HLA-A*24 and HLA-DRB1*11 alleles may be prognostic and predictive biomarkers for clinical benefit.
Anastasopoulou EA, Voutsas IF, Keramitsoglou T, Gouttefangeas C, Kalbacher H, Thanos A, Papamichail M, Perez SA, Baxevanis CN. Anastasopoulou EA, et al. Cancer Immunol Immunother. 2015 Sep;64(9):1123-36. doi: 10.1007/s00262-015-1717-1. Epub 2015 May 31. Cancer Immunol Immunother. 2015. PMID: 26026288 Free PMC article. Clinical Trial.
Primary analysis of a prospective, randomized, single-blinded phase II trial evaluating the HER2 peptide AE37 vaccine in breast cancer patients to prevent recurrence.
Mittendorf EA, Ardavanis A, Symanowski J, Murray JL, Shumway NM, Litton JK, Hale DF, Perez SA, Anastasopoulou EA, Pistamaltzian NF, Ponniah S, Baxevanis CN, von Hofe E, Papamichail M, Peoples GE. Mittendorf EA, et al. Among authors: anastasopoulou ea. Ann Oncol. 2016 Jul;27(7):1241-8. doi: 10.1093/annonc/mdw150. Epub 2016 Mar 30. Ann Oncol. 2016. PMID: 27029708 Free PMC article. Clinical Trial.
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