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2002 4
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2007 1
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Page 1
A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function.
Barouch-Bentov R, Che J, Lee CC, Yang Y, Herman A, Jia Y, Velentza A, Watson J, Sternberg L, Kim S, Ziaee N, Miller A, Jackson C, Fujimoto M, Young M, Batalov S, Liu Y, Warmuth M, Wiltshire T, Cooke MP, Sauer K. Barouch-Bentov R, et al. Among authors: velentza a. Mol Cell. 2009 Jan 16;33(1):43-52. doi: 10.1016/j.molcel.2008.12.024. Mol Cell. 2009. PMID: 19150426 Free PMC article.
Clinical stage EGFR inhibitors irreversibly alkylate Bmx kinase.
Hur W, Velentza A, Kim S, Flatauer L, Jiang X, Valente D, Mason DE, Suzuki M, Larson B, Zhang J, Zagorska A, Didonato M, Nagle A, Warmuth M, Balk SP, Peters EC, Gray NS. Hur W, et al. Among authors: velentza a. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5916-9. doi: 10.1016/j.bmcl.2008.07.062. Epub 2008 Jul 18. Bioorg Med Chem Lett. 2008. PMID: 18667312 Free PMC article.
Allosteric inhibitors of Bcr-abl-dependent cell proliferation.
Adrián FJ, Ding Q, Sim T, Velentza A, Sloan C, Liu Y, Zhang G, Hur W, Ding S, Manley P, Mestan J, Fabbro D, Gray NS. Adrián FJ, et al. Among authors: velentza a. Nat Chem Biol. 2006 Feb;2(2):95-102. doi: 10.1038/nchembio760. Epub 2006 Jan 15. Nat Chem Biol. 2006. PMID: 16415863
Discovery of a new class of synthetic protein kinase inhibitors that suppress selective aspects of glial activation and protect against beta-amyloid induced injury: a foundation for future medicinal chemistry efforts focused on targeting Alzheimer's disease progression.
Watterson DM, Velentza AV, Zasadzki M, Craft JM, Haiech J, Van Eldik LJ. Watterson DM, et al. Among authors: velentza av. J Mol Neurosci. 2003;20(3):411-23. doi: 10.1385/JMN:20:3:411. J Mol Neurosci. 2003. PMID: 14501026
Protein kinase involved in lung injury susceptibility: evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment.
Wainwright MS, Rossi J, Schavocky J, Crawford S, Steinhorn D, Velentza AV, Zasadzki M, Shirinsky V, Jia Y, Haiech J, Van Eldik LJ, Watterson DM. Wainwright MS, et al. Among authors: velentza av. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6233-8. doi: 10.1073/pnas.1031595100. Epub 2003 May 2. Proc Natl Acad Sci U S A. 2003. PMID: 12730364 Free PMC article.
14 results