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Fatty acid desaturation and lipoxygenase pathways support trained immunity.
Ferreira AV, Alarcon-Barrera JC, Domínguez-Andrés J, Bulut Ö, Kilic G, Debisarun PA, Röring RJ, Özhan HN, Terschlüsen E, Ziogas A, Kostidis S, Mohammed Y, Matzaraki V, Renieris G, Giamarellos-Bourboulis EJ, Netea MG, Giera M. Ferreira AV, et al. Nat Commun. 2023 Nov 15;14(1):7385. doi: 10.1038/s41467-023-43315-x. Nat Commun. 2023. PMID: 37968313 Free PMC article.
Dimethyl itaconate induces long-term innate immune responses and confers protection against infection.
Ferreira AV, Kostidis S, Groh LA, Koeken VACM, Bruno M, Baydemir I, Kilic G, Bulut Ö, Andriopoulou T, Spanou V, Synodinou KD, Gkavogianni T, Moorlag SJCFM, Charlotte de Bree L, Mourits VP, Matzaraki V, Koopman WJH, van de Veerdonk FL, Renieris G, Giera M, Giamarellos-Bourboulis EJ, Novakovic B, Domínguez-Andrés J. Ferreira AV, et al. Cell Rep. 2023 Jun 27;42(6):112658. doi: 10.1016/j.celrep.2023.112658. Epub 2023 Jun 16. Cell Rep. 2023. PMID: 37330914 Free article.
Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19.
Liu Z, Kilic G, Li W, Bulut O, Gupta MK, Zhang B, Qi C, Peng H, Tsay HC, Soon CF, Mekonnen YA, Ferreira AV, van der Made CI, van Cranenbroek B, Koenen HJPM, Simonetti E, Diavatopoulos D, de Jonge MI, Müller L, Schaal H, Ostermann PN, Cornberg M, Eiz-Vesper B, van de Veerdonk F, van Crevel R, Joosten LAB, Domínguez-Andrés J, Xu CJ, Netea MG, Li Y. Liu Z, et al. Front Immunol. 2022 Apr 6;13:838132. doi: 10.3389/fimmu.2022.838132. eCollection 2022. Front Immunol. 2022. PMID: 35464396 Free PMC article.
oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming.
Groh LA, Ferreira AV, Helder L, van der Heijden CDCC, Novakovic B, van de Westerlo E, Matzaraki V, Moorlag SJCFM, de Bree LC, Koeken VACM, Mourits VP, Keating ST, van Puffelen JH, Hoischen A, Joosten LAB, Netea MG, Koopman WJH, Riksen NP. Groh LA, et al. Among authors: ferreira av. Immunometabolism. 2021 Jun 30;3(3):e210025. doi: 10.20900/immunometab20210025. eCollection 2021. Immunometabolism. 2021. PMID: 34267957 Free PMC article.
Glutathione Metabolism Contributes to the Induction of Trained Immunity.
Ferreira AV, Koeken VACM, Matzaraki V, Kostidis S, Alarcon-Barrera JC, de Bree LCJ, Moorlag SJCFM, Mourits VP, Novakovic B, Giera MA, Netea MG, Domínguez-Andrés J. Ferreira AV, et al. Cells. 2021 Apr 21;10(5):971. doi: 10.3390/cells10050971. Cells. 2021. PMID: 33919212 Free PMC article.
In vitro induction of trained immunity in adherent human monocytes.
Domínguez-Andrés J, Arts RJW, Bekkering S, Bahrar H, Blok BA, de Bree LCJ, Bruno M, Bulut Ö, Debisarun PA, Dijkstra H, Cristina Dos Santos J, Ferreira AV, Flores-Gomez D, Groh LA, Grondman I, Helder L, Jacobs C, Jacobs L, Jansen T, Kilic G, Klück V, Koeken VACM, Lemmers H, Moorlag SJCFM, Mourits VP, van Puffelen JH, Rabold K, Röring RJ, Rosati D, Tercan H, van Tuijl J, Quintin J, van Crevel R, Riksen NP, Joosten LAB, Netea MG. Domínguez-Andrés J, et al. Among authors: ferreira av. STAR Protoc. 2021 Feb 24;2(1):100365. doi: 10.1016/j.xpro.2021.100365. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33718890 Free PMC article.
Lysine methyltransferase G9a is an important modulator of trained immunity.
Mourits VP, van Puffelen JH, Novakovic B, Bruno M, Ferreira AV, Arts RJ, Groh L, Crișan TO, Zwaag J, Jentho E, Kox M, Pickkers P, van de Veerdonk FL, Weis S, Oosterwijk E, Vermeulen SH, Netea MG, Joosten LA. Mourits VP, et al. Among authors: ferreira av. Clin Transl Immunology. 2021 Feb 18;10(2):e1253. doi: 10.1002/cti2.1253. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33708384 Free PMC article.
15 results