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Galunisertib downregulates mutant type I collagen expression and promotes MSCs osteogenesis in pediatric osteogenesis imperfecta.
Infante A, Alcorta-Sevillano N, Macías I, Cabodevilla L, Medhat D, Lafaver B, Crawford TK, Phillips CL, Bueno AM, Sagastizabal B, Arroyo M, Campino A, Gerovska D, Araúzo-Bravo M, Gener B, Rodríguez CI. Infante A, et al. Among authors: bueno am. Biomed Pharmacother. 2024 May 13;175:116725. doi: 10.1016/j.biopha.2024.116725. Online ahead of print. Biomed Pharmacother. 2024. PMID: 38744219 Free article.
Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro-osteogenic paracrine response: TERCELOI clinical trial.
Infante A, Gener B, Vázquez M, Olivares N, Arrieta A, Grau G, Llano I, Madero L, Bueno AM, Sagastizabal B, Gerovska D, Araúzo-Bravo MJ, Astigarraga I, Rodríguez CI. Infante A, et al. Clin Transl Med. 2021 Jan;11(1):e265. doi: 10.1002/ctm2.265. Clin Transl Med. 2021. PMID: 33463067 Free PMC article. Clinical Trial.
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