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Neoamphimedine circumvents metnase-enhanced DNA topoisomerase IIα activity through ATP-competitive inhibition.
Mar Drugs. 2011;9(11):2397-2408. doi: 10.3390/md9112397. Epub 2011 Nov 18.
Mar Drugs. 2011.
PMID: 22163192
Free PMC article.
DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe.
Ashley AK, Shrivastav M, Nie J, Amerin C, Troksa K, Glanzer JG, Liu S, Opiyo SO, Dimitrova DD, Le P, Sishc B, Bailey SM, Oakley GG, Nickoloff JA.
Ashley AK, et al.
DNA Repair (Amst). 2014 Sep;21:131-9. doi: 10.1016/j.dnarep.2014.04.008. Epub 2014 May 10.
DNA Repair (Amst). 2014.
PMID: 24819595
Free PMC article.
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Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.
Liu S, Opiyo SO, Manthey K, Glanzer JG, Ashley AK, Amerin C, Troksa K, Shrivastav M, Nickoloff JA, Oakley GG.
Liu S, et al.
Nucleic Acids Res. 2012 Nov;40(21):10780-94. doi: 10.1093/nar/gks849. Epub 2012 Sep 12.
Nucleic Acids Res. 2012.
PMID: 22977173
Free PMC article.
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