Ambrosini M - Search Results

1

Selective tumor antigen vaccine delivery to human CD169⁺ antigen-presenting cells using ganglioside-liposomes.

Affandi AJ, Grabowska J, Olesek K, Lopez Venegas M, Barbaria A, Rodríguez E, Mulder PPG, Pijffers HJ, Ambrosini M, Kalay H, O'Toole T, Zwart ES, Kazemier G, Nazmi K, Bikker FJ, Stöckl J, van den Eertwegh AJM, de Gruijl TD, Storm G, van Kooyk Y, den Haan JMM. Affandi AJ, et al. Among authors: ambrosini m. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27528-27539. doi: 10.1073/pnas.2006186117. Epub 2020 Oct 16. Proc Natl Acad Sci U S A. 2020. PMID: 33067394 Free PMC article.

2

Liposome induction of CD8⁺ T cell responses depends on CD169⁺ macrophages and Batf3-dependent dendritic cells and is enhanced by GM3 inclusion.

Grabowska J, Affandi AJ, van Dinther D, Nijen Twilhaar MK, Olesek K, Hoogterp L, Ambrosini M, Heijnen DAM, Klaase L, Hidalgo A, Asano K, Crocker PR, Storm G, van Kooyk Y, den Haan JMM. Grabowska J, et al. Among authors: ambrosini m. J Control Release. 2021 Mar 10;331:309-320. doi: 10.1016/j.jconrel.2021.01.029. Epub 2021 Jan 22. J Control Release. 2021. PMID: 33493613 Free article.

3

In situ Delivery of Tumor Antigen- and Adjuvant-Loaded Liposomes Boosts Antigen-Specific T-Cell Responses by Human Dermal Dendritic Cells.

Boks MA, Bruijns SCM, Ambrosini M, Kalay H, van Bloois L, Storm G, Gruijl T, van Kooyk Y. Boks MA, et al. Among authors: ambrosini m. J Invest Dermatol. 2015 Nov;135(11):2697-2704. doi: 10.1038/jid.2015.226. Epub 2015 Jun 17. J Invest Dermatol. 2015. PMID: 26083554 Free article.

4

Activation of CD8⁺ T Cell Responses after Melanoma Antigen Targeting to CD169⁺ Antigen Presenting Cells in Mice and Humans.

van Dinther D, Lopez Venegas M, Veninga H, Olesek K, Hoogterp L, Revet M, Ambrosini M, Kalay H, Stöckl J, van Kooyk Y, den Haan JMM. van Dinther D, et al. Among authors: ambrosini m. Cancers (Basel). 2019 Feb 5;11(2):183. doi: 10.3390/cancers11020183. Cancers (Basel). 2019. PMID: 30764534 Free PMC article.

5

Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets.

Duinkerken S, Horrevorts SK, Kalay H, Ambrosini M, Rutte L, de Gruijl TD, Garcia-Vallejo JJ, van Kooyk Y. Duinkerken S, et al. Among authors: ambrosini m. Theranostics. 2019 Aug 12;9(20):5797-5809. doi: 10.7150/thno.35059. eCollection 2019. Theranostics. 2019. PMID: 31534520 Free PMC article.

6

Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells.

Unger WW, van Beelen AJ, Bruijns SC, Joshi M, Fehres CM, van Bloois L, Verstege MI, Ambrosini M, Kalay H, Nazmi K, Bolscher JG, Hooijberg E, de Gruijl TD, Storm G, van Kooyk Y. Unger WW, et al. Among authors: ambrosini m. J Control Release. 2012 May 30;160(1):88-95. doi: 10.1016/j.jconrel.2012.02.007. Epub 2012 Feb 15. J Control Release. 2012. PMID: 22366522

7

Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells.

García-Vallejo JJ, Ambrosini M, Overbeek A, van Riel WE, Bloem K, Unger WW, Chiodo F, Bolscher JG, Nazmi K, Kalay H, van Kooyk Y. García-Vallejo JJ, et al. Among authors: ambrosini m. Mol Immunol. 2013 Apr;53(4):387-97. doi: 10.1016/j.molimm.2012.09.012. Epub 2012 Oct 24. Mol Immunol. 2013. PMID: 23103377

8

Topical rather than intradermal application of the TLR7 ligand imiquimod leads to human dermal dendritic cell maturation and CD8+ T-cell cross-priming.

Fehres CM, Bruijns SC, van Beelen AJ, Kalay H, Ambrosini M, Hooijberg E, Unger WW, de Gruijl TD, van Kooyk Y. Fehres CM, et al. Among authors: ambrosini m. Eur J Immunol. 2014 Aug;44(8):2415-24. doi: 10.1002/eji.201344094. Epub 2014 Jun 24. Eur J Immunol. 2014. PMID: 24825342 Free article.

9

Cross-presentation through langerin and DC-SIGN targeting requires different formulations of glycan-modified antigens.

Fehres CM, Kalay H, Bruijns SC, Musaafir SA, Ambrosini M, van Bloois L, van Vliet SJ, Storm G, Garcia-Vallejo JJ, van Kooyk Y. Fehres CM, et al. Among authors: ambrosini m. J Control Release. 2015 Apr 10;203:67-76. doi: 10.1016/j.jconrel.2015.01.040. Epub 2015 Feb 2. J Control Release. 2015. PMID: 25656175

10

In situ Delivery of Antigen to DC-SIGN(+)CD14(+) Dermal Dendritic Cells Results in Enhanced CD8(+) T-Cell Responses.

Fehres CM, van Beelen AJ, Bruijns SCM, Ambrosini M, Kalay H, Bloois LV, Unger WWJ, Garcia-Vallejo JJ, Storm G, de Gruijl TD, Kooyk YV. Fehres CM, et al. Among authors: ambrosini m. J Invest Dermatol. 2015 Sep;135(9):2228-2236. doi: 10.1038/jid.2015.152. Epub 2015 Apr 14. J Invest Dermatol. 2015. PMID: 25885805 Free article.

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