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Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2.
Hilligan KL, Namasivayam S, Clancy CS, Baker PJ, Old SI, Peluf V, Amaral EP, Oland SD, O'Mard D, Laux J, Cohen M, Garza NL, Lafont BAP, Johnson RF, Feng CG, Jankovic D, Lamiable O, Mayer-Barber KD, Sher A. Hilligan KL, et al. Among authors: amaral ep. Nat Commun. 2023 Dec 12;14(1):8229. doi: 10.1038/s41467-023-43447-0. Nat Commun. 2023. PMID: 38086794 Free PMC article.
Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk.
Mayer-Barber KD, Andrade BB, Oland SD, Amaral EP, Barber DL, Gonzales J, Derrick SC, Shi R, Kumar NP, Wei W, Yuan X, Zhang G, Cai Y, Babu S, Catalfamo M, Salazar AM, Via LE, Barry CE 3rd, Sher A. Mayer-Barber KD, et al. Among authors: amaral ep. Nature. 2014 Jul 3;511(7507):99-103. doi: 10.1038/nature13489. Epub 2014 Jun 25. Nature. 2014. PMID: 24990750 Free PMC article.
Co-infection of mice with SARS-CoV-2 and Mycobacterium tuberculosis limits early viral replication but does not affect mycobacterial loads.
Baker PJ, Amaral EP, Castro E, Bohrer AC, Torres-Juárez F, Jordan CM, Nelson CE, Barber DL, Johnson RF, Hilligan KL, Mayer-Barber KD. Baker PJ, et al. Among authors: amaral ep. Front Immunol. 2023 Sep 1;14:1240419. doi: 10.3389/fimmu.2023.1240419. eCollection 2023. Front Immunol. 2023. PMID: 37720210 Free PMC article.
BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility.
Amaral EP, Namasivayam S, Queiroz ATL, Fukutani E, Hilligan KL, Aberman K, Fisher L, Bomfim CCB, Kauffman K, Buchanan J, Santuo L, Gazzinelli-Guimaraes PH, Costa DL, Teixeira MA, Barreto-Duarte B, Rocha CG, Santana MF, Cordeiro-Santos M, Barber DL, Wilkinson RJ, Kramnik I, Igarashi K, Scriba T, Mayer-Barber KD, Andrade BB, Sher A. Amaral EP, et al. Nat Microbiol. 2024 Jan;9(1):120-135. doi: 10.1038/s41564-023-01523-7. Epub 2023 Dec 8. Nat Microbiol. 2024. PMID: 38066332 Free PMC article.
GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection.
Amaral EP, Foreman TW, Namasivayam S, Hilligan KL, Kauffman KD, Barbosa Bomfim CC, Costa DL, Barreto-Duarte B, Gurgel-Rocha C, Santana MF, Cordeiro-Santos M, Du Bruyn E, Riou C, Aberman K, Wilkinson RJ, Barber DL, Mayer-Barber KD, Andrade BB, Sher A. Amaral EP, et al. J Exp Med. 2022 Nov 7;219(11):e20220504. doi: 10.1084/jem.20220504. Epub 2022 Sep 7. J Exp Med. 2022. PMID: 36069923 Free PMC article.
Persistent Oxidative Stress and Inflammasome Activation in CD14highCD16- Monocytes From COVID-19 Patients.
Lage SL, Amaral EP, Hilligan KL, Laidlaw E, Rupert A, Namasivayan S, Rocco J, Galindo F, Kellogg A, Kumar P, Poon R, Wortmann GW, Shannon JP, Hickman HD, Lisco A, Manion M, Sher A, Sereti I. Lage SL, et al. Among authors: amaral ep. Front Immunol. 2022 Jan 14;12:799558. doi: 10.3389/fimmu.2021.799558. eCollection 2021. Front Immunol. 2022. PMID: 35095880 Free PMC article.
Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis.
Bomfim CCB, Fisher L, Amaral EP, Mittereder L, McCann K, Correa AAS, Namasivayam S, Swamydas M, Moayeri M, Weiss JM, Chari R, McVicar DW, Costa DL, D'Império Lima MR, Sher A. Bomfim CCB, et al. Among authors: amaral ep. Front Cell Infect Microbiol. 2022 May 2;12:862582. doi: 10.3389/fcimb.2022.862582. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35586249 Free PMC article.
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