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Metabolic Profiling of Thymic Epithelial Tumors Hints to a Strong Warburg Effect, Glutaminolysis and Precarious Redox Homeostasis as Potential Therapeutic Targets.
Alwahsh M, Knitsch R, Marchan R, Lambert J, Hoerner C, Zhang X, Schalke B, Lee DH, Bulut E, Graeter T, Ott G, Kurz KS, Preissler G, Schölch S, Farhat J, Yao Z, Sticht C, Ströbel P, Hergenröder R, Marx A, Belharazem D. Alwahsh M, et al. Cancers (Basel). 2022 Mar 18;14(6):1564. doi: 10.3390/cancers14061564. Cancers (Basel). 2022. PMID: 35326714 Free PMC article.
In Vitro Spatio-Temporal NMR Metabolomics of Living 3D Cell Models.
Knitsch R, AlWahsh M, Raschke H, Lambert J, Hergenröder R. Knitsch R, et al. Among authors: alwahsh m. Anal Chem. 2021 Oct 12;93(40):13485-13494. doi: 10.1021/acs.analchem.1c02221. Epub 2021 Sep 3. Anal Chem. 2021. PMID: 34478621 Free article.
Glycolytic flux control by drugging phosphoglycolate phosphatase.
Jeanclos E, Schlötzer J, Hadamek K, Yuan-Chen N, Alwahsh M, Hollmann R, Fratz S, Yesilyurt-Gerhards D, Frankenbach T, Engelmann D, Keller A, Kaestner A, Schmitz W, Neuenschwander M, Hergenröder R, Sotriffer C, von Kries JP, Schindelin H, Gohla A. Jeanclos E, et al. Among authors: alwahsh m. Nat Commun. 2022 Nov 11;13(1):6845. doi: 10.1038/s41467-022-34228-2. Nat Commun. 2022. PMID: 36369173 Free PMC article.
Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth.
Keller M, Rohlf K, Glotzbach A, Leonhardt G, Lüke S, Derksen K, Demirci Ö, Göçener D, AlWahsh M, Lambert J, Lindskog C, Schmidt M, Brenner W, Baumann M, Zent E, Zischinsky ML, Hellwig B, Madjar K, Rahnenführer J, Overbeck N, Reinders J, Cadenas C, Hengstler JG, Edlund K, Marchan R. Keller M, et al. Among authors: alwahsh m. J Exp Clin Cancer Res. 2023 Jan 20;42(1):25. doi: 10.1186/s13046-022-02578-w. J Exp Clin Cancer Res. 2023. PMID: 36670508 Free PMC article.
17 results