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Higher frequency of Human herpesvirus-6 (HHV-6) viral DNA simultaneously with low frequency of Epstein-Barr virus (EBV) viral DNA in a cohort of multiple sclerosis patients from Rio de Janeiro, Brazil.
Pereira JG, Leon LAA, de Almeida NAA, Raposo-Vedovi JV, Fontes-Dantas FL, Farinhas JGD, Pereira VCSR, Alves-Leon SV, de Paula VS. Pereira JG, et al. Among authors: alves leon sv. Mult Scler Relat Disord. 2023 Aug;76:104747. doi: 10.1016/j.msard.2023.104747. Epub 2023 May 1. Mult Scler Relat Disord. 2023. PMID: 37267685
SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice.
Fontes-Dantas FL, Fernandes GG, Gutman EG, De Lima EV, Antonio LS, Hammerle MB, Mota-Araujo HP, Colodeti LC, Araújo SMB, Froz GM, da Silva TN, Duarte LA, Salvio AL, Pires KL, Leon LAA, Vasconcelos CCF, Romão L, Savio LEB, Silva JL, da Costa R, Clarke JR, Da Poian AT, Alves-Leon SV, Passos GF, Figueiredo CP. Fontes-Dantas FL, et al. Cell Rep. 2023 Mar 28;42(3):112189. doi: 10.1016/j.celrep.2023.112189. Epub 2023 Feb 17. Cell Rep. 2023. PMID: 36857178 Free PMC article.
AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models.
Selles MC, Fortuna JTS, Cercato MC, Santos LE, Domett L, Bitencourt ALB, Carraro MF, Souza AS, Janickova H, Azevedo CV, Campos HC, de Souza JM, Alves-Leon S, Prado VF, Prado MAM, Epstein AL, Salvetti A, Longo BM, Arancio O, Klein WL, Sebollela A, De Felice FG, Jerusalinsky DA, Ferreira ST. Selles MC, et al. Mol Ther. 2023 Feb 1;31(2):409-419. doi: 10.1016/j.ymthe.2022.11.002. Epub 2022 Nov 11. Mol Ther. 2023. PMID: 36369741 Free PMC article.
Long COVID: plasma levels of neurofilament light chain in mild COVID-19 patients with neurocognitive symptoms.
Gutman EG, Salvio AL, Fernandes RA, Duarte LA, Raposo-Vedovi JV, Alcaraz HF, Teixeira MA, Passos GF, de Medeiros KQM, Hammerle MB, Pires KL, Vasconcelos CCF, Leon LAA, Figueiredo CP, Alves-Leon SV. Gutman EG, et al. Among authors: alves leon sv. Mol Psychiatry. 2024 Apr 27. doi: 10.1038/s41380-024-02554-0. Online ahead of print. Mol Psychiatry. 2024. PMID: 38678084
Molecular Mimicry between SARS-CoV-2 Proteins and Human Self-Antigens Related with Autoimmune Central Nervous System (CNS) Disorders.
Gutman EG, Fernandes RA, Raposo-Vedovi JV, Salvio AL, Duarte LA, Tardim CF, Costa VGC, Pereira VCSR, Bahia PRV, da Silva MM, Fontes-Dantas FL, Alves-Leon SV. Gutman EG, et al. Among authors: alves leon sv. Microorganisms. 2023 Dec 1;11(12):2902. doi: 10.3390/microorganisms11122902. Microorganisms. 2023. PMID: 38138047 Free PMC article.
97 results