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Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites.
Stampolaki M, Malwal SR, Alvarez-Cabrera N, Gao Z, Moniruzzaman M, Babii SO, Naziris N, Rey-Cibati A, Valladares-Delgado M, Turcu AL, Baek KH, Phan TN, Lee H, Alcaraz M, Watson S, van der Watt M, Coertzen D, Efstathiou N, Chountoulesi M, Shoen CM, Papanastasiou IP, Brea J, Cynamon MH, Birkholtz LM, Kremer L, No JH, Vázquez S, Benaim G, Demetzos C, Zgurskaya HI, Dick T, Oldfield E, Kolocouris AD. Stampolaki M, et al. Among authors: alvarez cabrera n. ACS Infect Dis. 2023 Feb 10;9(2):342-364. doi: 10.1021/acsinfecdis.2c00537. Epub 2023 Jan 27. ACS Infect Dis. 2023. PMID: 36706233 Free PMC article.
Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance.
Williams JT, Haiderer ER, Coulson GB, Conner KN, Ellsworth E, Chen C, Alvarez-Cabrera N, Li W, Jackson M, Dick T, Abramovitch RB. Williams JT, et al. Among authors: alvarez cabrera n. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e00547-19. doi: 10.1128/AAC.00547-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31405862 Free PMC article.
Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations.
Sarathy J, Blanc L, Alvarez-Cabrera N, O'Brien P, Dias-Freedman I, Mina M, Zimmerman M, Kaya F, Ho Liang HP, Prideaux B, Dietzold J, Salgame P, Savic RM, Linderman J, Kirschner D, Pienaar E, Dartois V. Sarathy J, et al. Among authors: alvarez cabrera n. Antimicrob Agents Chemother. 2019 Apr 25;63(5):e02516-18. doi: 10.1128/AAC.02516-18. Print 2019 May. Antimicrob Agents Chemother. 2019. PMID: 30803965 Free PMC article.
Investigation of ( S)-(-)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin Synthase.
Bockman MR, Engelhart CA, Cramer JD, Howe MD, Mishra NK, Zimmerman M, Larson P, Alvarez-Cabrera N, Park SW, Boshoff HIM, Bean JM, Young VG Jr, Ferguson DM, Dartois V, Jarrett JT, Schnappinger D, Aldrich CC. Bockman MR, et al. Among authors: alvarez cabrera n. ACS Infect Dis. 2019 Apr 12;5(4):598-617. doi: 10.1021/acsinfecdis.8b00345. Epub 2019 Feb 4. ACS Infect Dis. 2019. PMID: 30652474 Free PMC article.
Impact of immunopathology on the antituberculous activity of pyrazinamide.
Blanc L, Sarathy JP, Alvarez Cabrera N, O'Brien P, Dias-Freedman I, Mina M, Sacchettini J, Savic RM, Gengenbacher M, Podell BK, Prideaux B, Ioerger T, Dick T, Dartois V. Blanc L, et al. Among authors: alvarez cabrera n. J Exp Med. 2018 Aug 6;215(8):1975-1986. doi: 10.1084/jem.20180518. Epub 2018 Jul 17. J Exp Med. 2018. PMID: 30018074 Free PMC article.