Alvarez S - Search Results

1

Nanopore-mediated protein delivery enabling three-color single-molecule tracking in living cells.

Chen Z, Cao Y, Lin CW, Alvarez S, Oh D, Yang P, Groves JT. Chen Z, et al. Among authors: alvarez s. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2012229118. doi: 10.1073/pnas.2012229118. Proc Natl Acad Sci U S A. 2021. PMID: 33495347 Free PMC article.

2

Relating cellular signaling timescales to single-molecule kinetics: A first-passage time analysis of Ras activation by SOS.

Huang WYC, Alvarez S, Kondo Y, Kuriyan J, Groves JT. Huang WYC, et al. Among authors: alvarez s. Proc Natl Acad Sci U S A. 2021 Nov 9;118(45):e2103598118. doi: 10.1073/pnas.2103598118. Proc Natl Acad Sci U S A. 2021. PMID: 34740968 Free PMC article.

3

Stochasticity and positive feedback enable enzyme kinetics at the membrane to sense reaction size.

Lee AA, Huang WYC, Hansen SD, Kim NH, Alvarez S, Groves JT. Lee AA, et al. Among authors: alvarez s. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2103626118. doi: 10.1073/pnas.2103626118. Proc Natl Acad Sci U S A. 2021. PMID: 34789575 Free PMC article.

4

Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate.

Lee YK, Low-Nam ST, Chung JK, Hansen SD, Lam HYM, Alvarez S, Groves JT. Lee YK, et al. Among authors: alvarez s. Nat Commun. 2017 Apr 28;8:15061. doi: 10.1038/ncomms15061. Nat Commun. 2017. PMID: 28452363 Free PMC article.

5

K-Ras4B Remains Monomeric on Membranes over a Wide Range of Surface Densities and Lipid Compositions.

Chung JK, Lee YK, Denson JP, Gillette WK, Alvarez S, Stephen AG, Groves JT. Chung JK, et al. Among authors: alvarez s. Biophys J. 2018 Jan 9;114(1):137-145. doi: 10.1016/j.bpj.2017.10.042. Biophys J. 2018. PMID: 29320680 Free PMC article.

6

A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS.

Huang WYC, Alvarez S, Kondo Y, Lee YK, Chung JK, Lam HYM, Biswas KH, Kuriyan J, Groves JT. Huang WYC, et al. Among authors: alvarez s. Science. 2019 Mar 8;363(6431):1098-1103. doi: 10.1126/science.aau5721. Epub 2019 Mar 7. Science. 2019. PMID: 30846600 Free PMC article.

7

Raf promotes dimerization of the Ras G-domain with increased allosteric connections.

Packer MR, Parker JA, Chung JK, Li Z, Lee YK, Cookis T, Guterres H, Alvarez S, Hossain MA, Donnelly DP, Agar JN, Makowski L, Buck M, Groves JT, Mattos C. Packer MR, et al. Among authors: alvarez s. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2015648118. doi: 10.1073/pnas.2015648118. Proc Natl Acad Sci U S A. 2021. PMID: 33653954 Free PMC article.

8

A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane.

Lin CW, Nocka LM, Stinger BL, DeGrandchamp JB, Lew LJN, Alvarez S, Phan HT, Kondo Y, Kuriyan J, Groves JT. Lin CW, et al. Among authors: alvarez s. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2122531119. doi: 10.1073/pnas.2122531119. Epub 2022 May 4. Proc Natl Acad Sci U S A. 2022. PMID: 35507881 Free PMC article.

9

One-way membrane trafficking of SOS in receptor-triggered Ras activation.

Christensen SM, Tu HL, Jun JE, Alvarez S, Triplet MG, Iwig JS, Yadav KK, Bar-Sagi D, Roose JP, Groves JT. Christensen SM, et al. Among authors: alvarez s. Nat Struct Mol Biol. 2016 Sep;23(9):838-46. doi: 10.1038/nsmb.3275. Epub 2016 Aug 8. Nat Struct Mol Biol. 2016. PMID: 27501536 Free PMC article.

10

Real-World Treatment Patterns Among Patients with Type 2 Diabetes Mellitus Initiating Treatment with Oral Semaglutide.

Swift C, Frazer MS, Gronroos NN, Sargent A, Leszko M, Buysman E, Alvarez S, Dunn TJ, Noone J, Guevarra M. Swift C, et al. Among authors: alvarez s. Diabetes Ther. 2024 May 9. doi: 10.1007/s13300-024-01589-4. Online ahead of print. Diabetes Ther. 2024. PMID: 38722496

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

1,240 results

Search Page