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Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy.
Hingorani DV, Allevato MM, Camargo MF, Lesperance J, Quraishi MA, Aguilera J, Franiak-Pietryga I, Scanderbeg DJ, Wang Z, Molinolo AA, Alvarado D, Sharabi AB, Bui JD, Cohen EEW, Adams SR, Gutkind JS, Advani SJ. Hingorani DV, et al. Among authors: alvarado d. Nat Commun. 2022 Jul 5;13(1):3869. doi: 10.1038/s41467-022-31601-z. Nat Commun. 2022. PMID: 35790753 Free PMC article.
Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer.
Wang Z, Goto Y, Allevato MM, Wu VH, Saddawi-Konefka R, Gilardi M, Alvarado D, Yung BS, O'Farrell A, Molinolo AA, Duvvuri U, Grandis JR, Califano JA, Cohen EEW, Gutkind JS. Wang Z, et al. Among authors: alvarado d. Nat Commun. 2021 Apr 22;12(1):2383. doi: 10.1038/s41467-021-22619-w. Nat Commun. 2021. PMID: 33888713 Free PMC article.
Structural basis for ligand reception by anaplastic lymphoma kinase.
Li T, Stayrook SE, Tsutsui Y, Zhang J, Wang Y, Li H, Proffitt A, Krimmer SG, Ahmed M, Belliveau O, Walker IX, Mudumbi KC, Suzuki Y, Lax I, Alvarado D, Lemmon MA, Schlessinger J, Klein DE. Li T, et al. Among authors: alvarado d. Nature. 2021 Dec;600(7887):148-152. doi: 10.1038/s41586-021-04141-7. Epub 2021 Nov 24. Nature. 2021. PMID: 34819665 Free PMC article.
Development of CDX-527: a bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy.
Vitale LA, He LZ, Thomas LJ, Wasiuk A, O'Neill T, Widger J, Crocker A, Mills-Chen L, Forsberg E, Weidlick J, Patterson C, Hammond RA, Boyer J, Sisson C, Alvarado D, Goldstein J, Marsh HC Jr, Keler T. Vitale LA, et al. Among authors: alvarado d. Cancer Immunol Immunother. 2020 Oct;69(10):2125-2137. doi: 10.1007/s00262-020-02610-y. Epub 2020 May 25. Cancer Immunol Immunother. 2020. PMID: 32451681 Free PMC article.
138 results