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Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry.
Nguyen TT, Shin DH, Sohoni S, Singh SK, Rivera-Molina Y, Jiang H, Fan X, Gumin J, Lang FF, Alvarez-Breckenridge C, Godoy-Vitorino F, Zhu L, Zheng WJ, Zhai L, Ladomersky E, Lauing KL, Alonso MM, Wainwright DA, Gomez-Manzano C, Fueyo J. Nguyen TT, et al. Among authors: alonso mm. J Immunother Cancer. 2022 Jul;10(7):e004935. doi: 10.1136/jitc-2022-004935. J Immunother Cancer. 2022. PMID: 35902132 Free PMC article.
Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas.
Jiang H, Shin DH, Nguyen TT, Fueyo J, Fan X, Henry V, Carrillo CC, Yi Y, Alonso MM, Collier TL, Yuan Y, Lang FF, Gomez-Manzano C. Jiang H, et al. Among authors: alonso mm. Clin Cancer Res. 2019 Nov 15;25(22):6801-6814. doi: 10.1158/1078-0432.CCR-19-0405. Epub 2019 Aug 27. Clin Cancer Res. 2019. PMID: 31455679 Free PMC article.
ICOVIR-5 shows E2F1 addiction and potent antiglioma effect in vivo.
Alonso MM, Cascallo M, Gomez-Manzano C, Jiang H, Bekele BN, Perez-Gimenez A, Lang FF, Piao Y, Alemany R, Fueyo J. Alonso MM, et al. Cancer Res. 2007 Sep 1;67(17):8255-63. doi: 10.1158/0008-5472.CAN-06-4675. Cancer Res. 2007. PMID: 17804740
160 results