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Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans.
Miyata T, Wu X, Fan X, Huang E, Sanz-Garcia C, Ross CKC, Roychowdhury S, Bellar A, McMullen MR, Dasarathy J, Allende DS, Caballeria J, Sancho-Bru P, McClain CJ, Mitchell M, McCullough AJ, Radaeva S, Barton B, Szabo G, Dasarathy S, Nagy LE. Miyata T, et al. Among authors: allende ds. JCI Insight. 2021 Feb 22;6(4):e140180. doi: 10.1172/jci.insight.140180. JCI Insight. 2021. PMID: 33616081 Free PMC article.
Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome.
Wang M, Osborn LJ, Jain S, Meng X, Weakley A, Yan J, Massey WJ, Varadharajan V, Horak A, Banerjee R, Allende DS, Chan ER, Hajjar AM, Wang Z, Dimas A, Zhao A, Nagashima K, Cheng AG, Higginbottom S, Hazen SL, Brown JM, Fischbach MA. Wang M, et al. Among authors: allende ds. Cell. 2023 Jun 22;186(13):2839-2852.e21. doi: 10.1016/j.cell.2023.05.037. Cell. 2023. PMID: 37352836
A Pilot Genome-Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH.
Gawrieh S, Guo X, Tan J, Lauzon M, Taylor KD, Loomba R, Cummings OW, Pillai S, Bhatnagar P, Kowdley KV, Yates K, Wilson LA, Chen YI, Rotter JI, Chalasani N; NASH Clinical Research Network. Gawrieh S, et al. Hepatol Commun. 2019 Nov 3;3(12):1571-1584. doi: 10.1002/hep4.1439. eCollection 2019 Dec. Hepatol Commun. 2019. PMID: 31832568 Free PMC article.
Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH.
Loomba R, Neuschwander-Tetri BA, Sanyal A, Chalasani N, Diehl AM, Terrault N, Kowdley K, Dasarathy S, Kleiner D, Behling C, Lavine J, Van Natta M, Middleton M, Tonascia J, Sirlin C; NASH Clinical Research Network. Loomba R, et al. Hepatology. 2020 Oct;72(4):1219-1229. doi: 10.1002/hep.31121. Epub 2020 Oct 9. Hepatology. 2020. PMID: 31965579 Free PMC article. Clinical Trial.
Inhibition of IRAK4 kinase activity improves ethanol-induced liver injury in mice.
Wang H, Zhou H, Zhang Q, Poulsen KL, Taylor V, McMullen MR, Czarnecki D, Dasarathy D, Yu M, Liao Y, Allende DS, Chen X, Hong L, Zhao J, Yang J, Nagy LE, Li X. Wang H, et al. Among authors: allende ds. J Hepatol. 2020 Dec;73(6):1470-1481. doi: 10.1016/j.jhep.2020.07.016. Epub 2020 Jul 16. J Hepatol. 2020. PMID: 32682051 Free PMC article.
Hepatobiliary malignancies have distinct peripheral myeloid-derived suppressor cell signatures and tumor myeloid cell profiles.
Bayik D, Lauko AJ, Roversi GA, Serbinowski E, Acevedo-Moreno LA, Lanigan C, Orujov M, Lo A, Alban TJ, Kim A, Silver DJ, Nagy LE, Brown JM, Allende DS, Aucejo FN, Lathia JD. Bayik D, et al. Among authors: allende ds. Sci Rep. 2020 Nov 2;10(1):18848. doi: 10.1038/s41598-020-75881-1. Sci Rep. 2020. PMID: 33139767 Free PMC article.
103 results