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Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability.
Välimäki N, Kuisma H, Pasanen A, Heikinheimo O, Sjöberg J, Bützow R, Sarvilinna N, Heinonen HR, Tolvanen J, Bramante S, Tanskanen T, Auvinen J, Uimari O, Alkodsi A, Lehtonen R, Kaasinen E, Palin K, Aaltonen LA. Välimäki N, et al. Among authors: alkodsi a. Elife. 2018 Sep 18;7:e37110. doi: 10.7554/eLife.37110. Elife. 2018. PMID: 30226466 Free PMC article.
Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans.
Kaasinen E, Kuismin O, Rajamäki K, Ristolainen H, Aavikko M, Kondelin J, Saarinen S, Berta DG, Katainen R, Hirvonen EAM, Karhu A, Taira A, Tanskanen T, Alkodsi A, Taipale M, Morgunova E, Franssila K, Lehtonen R, Mäkinen M, Aittomäki K, Palotie A, Kurki MI, Pietiläinen O, Hilpert M, Saarentaus E, Niinimäki J, Junttila J, Kaikkonen K, Vahteristo P, Skoda RC, Seppänen MRJ, Eklund KK, Taipale J, Kilpivaara O, Aaltonen LA. Kaasinen E, et al. Among authors: alkodsi a. Nat Commun. 2019 Mar 19;10(1):1252. doi: 10.1038/s41467-019-09198-7. Nat Commun. 2019. PMID: 30890702 Free PMC article.
Identifying differentially methylated sites in samples with varying tumor purity.
Häkkinen A, Alkodsi A, Facciotto C, Zhang K, Kaipio K, Leppä S, Carpén O, Grénman S, Hynninen J, Hietanen S, Lehtonen R, Hautaniemi S. Häkkinen A, et al. Among authors: alkodsi a. Bioinformatics. 2018 Sep 15;34(18):3078-3085. doi: 10.1093/bioinformatics/bty310. Bioinformatics. 2018. PMID: 29912358
PRISM: recovering cell-type-specific expression profiles from individual composite RNA-seq samples.
Häkkinen A, Zhang K, Alkodsi A, Andersson N, Erkan EP, Dai J, Kaipio K, Lamminen T, Mansuri N, Huhtinen K, Vähärautio A, Carpén O, Hynninen J, Hietanen S, Lehtonen R, Hautaniemi S. Häkkinen A, et al. Among authors: alkodsi a. Bioinformatics. 2021 Sep 29;37(18):2882-2888. doi: 10.1093/bioinformatics/btab178. Bioinformatics. 2021. PMID: 33720334 Free PMC article.
Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs).
Kjällquist U, Erlandsson R, Tobin NP, Alkodsi A, Ullah I, Stålhammar G, Karlsson E, Hatschek T, Hartman J, Linnarsson S, Bergh J. Kjällquist U, et al. Among authors: alkodsi a. BMC Cancer. 2018 Feb 12;18(1):174. doi: 10.1186/s12885-018-4021-6. BMC Cancer. 2018. PMID: 29433456 Free PMC article.
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