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Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.
Georgiadou E, Muralidharan C, Martinez M, Chabosseau P, Akalestou E, Tomas A, Wern FYS, Stylianides T, Wretlind A, Legido-Quigley C, Jones B, Lopez-Noriega L, Xu Y, Gu G, Alsabeeh N, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Leclerc I, Ali Y, Soleimanpour SA, Linnemann AK, Rodriguez TA, Rutter GA. Georgiadou E, et al. Among authors: ali y. Diabetes. 2022 Jul 1;71(7):1472-1489. doi: 10.2337/db21-0800. Diabetes. 2022. PMID: 35472764 Free PMC article.
Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes.
Zheng X, Ho QWC, Chua M, Stelmashenko O, Yeo XY, Muralidharan S, Torta F, Chew EGY, Lian MM, Foo JN, Jung S, Wong SH, Tan NS, Tong N, Rutter GA, Wenk MR, Silver DL, Berggren PO, Ali Y. Zheng X, et al. Among authors: ali y. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2113074119. doi: 10.1073/pnas.2113074119. Epub 2022 Mar 7. Proc Natl Acad Sci U S A. 2022. PMID: 35254894 Free PMC article.
Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.
Yu V, Yong F, Marta A, Khadayate S, Osakwe A, Bhattacharya S, Varghese SS, Chabosseau P, Tabibi SM, Chen K, Georgiadou E, Parveen N, Suleiman M, Stamoulis Z, Marselli L, De Luca C, Tesi M, Ostinelli G, Delgadillo-Silva L, Wu X, Hatanaka Y, Montoya A, Elliott J, Patel B, Demchenko N, Whilding C, Hajkova P, Shliaha P, Kramer H, Ali Y, Marchetti P, Sladek R, Dhawan S, Withers DJ, Rutter GA, Millership SJ. Yu V, et al. Among authors: ali y. Diabetologia. 2024 Jun;67(6):1079-1094. doi: 10.1007/s00125-024-06123-6. Epub 2024 Mar 21. Diabetologia. 2024. PMID: 38512414 Free PMC article.
Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes.
Åvall K, Ali Y, Leibiger IB, Leibiger B, Moede T, Paschen M, Dicker A, Daré E, Köhler M, Ilegems E, Abdulreda MH, Graham M, Crooke RM, Tay VS, Refai E, Nilsson SK, Jacob S, Selander L, Berggren PO, Juntti-Berggren L. Åvall K, et al. Among authors: ali y. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2611-9. doi: 10.1073/pnas.1423849112. Epub 2015 May 4. Proc Natl Acad Sci U S A. 2015. PMID: 25941406 Free PMC article.
Islet macrophages are associated with islet vascular remodeling and compensatory hyperinsulinemia during diabetes.
Chittezhath M, Gunaseelan D, Zheng X, Hasan R, Tay VSY, Lim ST, Wang X, Berggren PO, Bornstein S, Boehm B, Ruedl C, Ali Y. Chittezhath M, et al. Among authors: ali y. Am J Physiol Endocrinol Metab. 2019 Dec 1;317(6):E1108-E1120. doi: 10.1152/ajpendo.00248.2019. Epub 2019 Oct 1. Am J Physiol Endocrinol Metab. 2019. PMID: 31573842 Free article.
Islet Transplantation to the Anterior Chamber of the Eye-A Future Treatment Option for Insulin-Deficient Type-2 Diabetics? A Case Report from a Nonhuman Type-2 Diabetic Primate.
Tun SBB, Chua M, Hasan R, Köhler M, Zheng X, Ali Y, Abdulreda MH, Juntti-Berggren L, Barathi VA, Berggren PO. Tun SBB, et al. Among authors: ali y. Cell Transplant. 2020 Jan-Dec;29:963689720913256. doi: 10.1177/0963689720913256. Cell Transplant. 2020. PMID: 32264703 Free PMC article.
768 results