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Structural dynamics and anti-biofilm screening of novel imidazole derivative to explore their anti-biofilm inhibition mechanism against Pseudomonas Aeruginosa.
Mehmood S, Hussain M, Bux K, Hussain Z, Raza Shah M, Ali Jakhrani M, Ali Channar P, Begum I, Saboor R, Yildiz CB, Ali K, Herwig R. Mehmood S, et al. Among authors: ali channar p. J Biomol Struct Dyn. 2024 Feb 22:1-15. doi: 10.1080/07391102.2024.2317983. Online ahead of print. J Biomol Struct Dyn. 2024. PMID: 38385459
Synthesis, X-ray, Hirshfeld surface analysis, exploration of DNA binding, urease enzyme inhibition and anticancer activities of novel adamantane-naphthyl thiourea conjugate.
Arshad N, Saeed A, Perveen F, Ujan R, Farooqi SI, Ali Channar P, Shabir G, El-Seedi HR, Javed A, Yamin M, Bolte M, Hökelek T. Arshad N, et al. Among authors: ali channar p. Bioorg Chem. 2021 Apr;109:104707. doi: 10.1016/j.bioorg.2021.104707. Epub 2021 Feb 9. Bioorg Chem. 2021. PMID: 33639362
Identification of novel C-2 symmetric Bis-Azo-Azamethine molecules as competitive inhibitors of mushroom tyrosinase and free radical scavengers: synthesis, kinetics, and molecular docking studies.
Saeed A, Ahmed A, Ali Channar P, Shabir G, Hassan A, Zia-Ur-Rehman, Abbas Q, Hassan M, Raza H, Seo SY, El-Seedi HR. Saeed A, et al. Among authors: ali channar p. J Biomol Struct Dyn. 2022 Jul;40(10):4419-4428. doi: 10.1080/07391102.2020.1857841. Epub 2020 Dec 20. J Biomol Struct Dyn. 2022. PMID: 33342351
1-(2-Hydroxy-5-((trimethylsilyl)ethynyl)phenyl)ethanone based α,β-unsaturated derivatives an alternate to non-sulfonamide carbonic anhydrase II inhibitors, synthesis via Sonogashira coupling, binding analysis, Lipinsk's rule validation.
Mahar J, Saeed A, Belfield KD, Ali Larik F, Ali Channar P, Ali Kazi M, Abbas Q, Hassan M, Raza H, Seo SY. Mahar J, et al. Among authors: ali channar p. Bioorg Chem. 2019 Mar;84:170-176. doi: 10.1016/j.bioorg.2018.11.031. Epub 2018 Nov 24. Bioorg Chem. 2019. PMID: 30502628
Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysis.
Sajid-Ur-Rehman, Saeed A, Saddique G, Ali Channar P, Ali Larik F, Abbas Q, Hassan M, Raza H, Fattah TA, Seo SY. Sajid-Ur-Rehman, et al. Among authors: ali channar p. Bioorg Med Chem. 2018 Jul 23;26(12):3707-3715. doi: 10.1016/j.bmc.2018.06.002. Epub 2018 Jun 2. Bioorg Med Chem. 2018. PMID: 29884581