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Inhibition of 2-hydroxyglutarate elicits metabolic reprogramming and mutant IDH1 glioma immunity in mice.
Kadiyala P, Carney SV, Gauss JC, Garcia-Fabiani MB, Haase S, Alghamri MS, Núñez FJ, Liu Y, Yu M, Taher A, Nunez FM, Li D, Edwards MB, Kleer CG, Appelman H, Sun Y, Zhao L, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Kadiyala P, et al. Among authors: alghamri ms. J Clin Invest. 2021 Feb 15;131(4):e139542. doi: 10.1172/JCI139542. J Clin Invest. 2021. PMID: 33332283 Free PMC article.
Melanoma induced immunosuppression is mediated by hematopoietic dysregulation.
Kamran N, Li Y, Sierra M, Alghamri MS, Kadiyala P, Appelman HD, Edwards M, Lowenstein PR, Castro MG. Kamran N, et al. Among authors: alghamri ms. Oncoimmunology. 2017 Dec 14;7(3):e1408750. doi: 10.1080/2162402X.2017.1408750. eCollection 2018. Oncoimmunology. 2017. PMID: 29399415 Free PMC article.
Current state and future prospects of immunotherapy for glioma.
Kamran N, Alghamri MS, Nunez FJ, Shah D, Asad AS, Candolfi M, Altshuler D, Lowenstein PR, Castro MG. Kamran N, et al. Among authors: alghamri ms. Immunotherapy. 2018 Feb 1;10(4):317-339. doi: 10.2217/imt-2017-0122. Immunotherapy. 2018. PMID: 29421984 Free PMC article. Review.
IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.
Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG. Núñez FJ, et al. Among authors: alghamri ms. Sci Transl Med. 2019 Feb 13;11(479):eaaq1427. doi: 10.1126/scitranslmed.aaq1427. Sci Transl Med. 2019. PMID: 30760578 Free PMC article.
Prospects of biological and synthetic pharmacotherapies for glioblastoma.
Altshuler DB, Kadiyala P, Nuñez FJ, Nuñez FM, Carney S, Alghamri MS, Garcia-Fabiani MB, Asad AS, Nicola Candia AJ, Candolfi M, Lahann J, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Altshuler DB, et al. Among authors: alghamri ms. Expert Opin Biol Ther. 2020 Mar;20(3):305-317. doi: 10.1080/14712598.2020.1713085. Epub 2020 Jan 20. Expert Opin Biol Ther. 2020. PMID: 31959027 Free PMC article. Review.
Immunotherapy for gliomas: shedding light on progress in preclinical and clinical development.
Garcia-Fabiani MB, Ventosa M, Comba A, Candolfi M, Nicola Candia AJ, Alghamri MS, Kadiyala P, Carney S, Faisal SM, Schwendeman A, Moon JJ, Scheetz L, Lahann J, Mauser A, Lowenstein PR, Castro MG. Garcia-Fabiani MB, et al. Among authors: alghamri ms. Expert Opin Investig Drugs. 2020 Jul;29(7):659-684. doi: 10.1080/13543784.2020.1768528. Epub 2020 Jun 4. Expert Opin Investig Drugs. 2020. PMID: 32400216 Review.
Current Approaches for Glioma Gene Therapy and Virotherapy.
Banerjee K, Núñez FJ, Haase S, McClellan BL, Faisal SM, Carney SV, Yu J, Alghamri MS, Asad AS, Candia AJN, Varela ML, Candolfi M, Lowenstein PR, Castro MG. Banerjee K, et al. Among authors: alghamri ms. Front Mol Neurosci. 2021 Mar 11;14:621831. doi: 10.3389/fnmol.2021.621831. eCollection 2021. Front Mol Neurosci. 2021. PMID: 33790740 Free PMC article. Review.
29 results