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Bisphosphonate derivatized polyurethanes resist calcification.
Alferiev I, Vyavahare N, Song C, Connolly J, Hinson JT, Lu Z, Tallapragada S, Bianco R, Levy R. Alferiev I, et al. Biomaterials. 2001 Oct;22(19):2683-93. doi: 10.1016/s0142-9612(01)00010-2. Biomaterials. 2001. PMID: 11519788
Triglycidylamine crosslinking of porcine aortic valve cusps or bovine pericardium results in improved biocompatibility, biomechanics, and calcification resistance: chemical and biological mechanisms.
Connolly JM, Alferiev I, Clark-Gruel JN, Eidelman N, Sacks M, Palmatory E, Kronsteiner A, Defelice S, Xu J, Ohri R, Narula N, Vyavahare N, Levy RJ. Connolly JM, et al. Am J Pathol. 2005 Jan;166(1):1-13. doi: 10.1016/S0002-9440(10)62227-4. Am J Pathol. 2005. PMID: 15631995 Free PMC article.
Site specific gene delivery in the cardiovascular system.
Fishbein I, Stachelek SJ, Connolly JM, Wilensky RL, Alferiev I, Levy RJ. Fishbein I, et al. J Control Release. 2005 Dec 5;109(1-3):37-48. doi: 10.1016/j.jconrel.2005.09.031. Epub 2005 Nov 17. J Control Release. 2005. PMID: 16298010 Review.
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