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Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
Eser S, Reiff N, Messer M, Seidler B, Gottschalk K, Dobler M, Hieber M, Arbeiter A, Klein S, Kong B, Michalski CW, Schlitter AM, Esposito I, Kind AJ, Rad L, Schnieke AE, Baccarini M, Alessi DR, Rad R, Schmid RM, Schneider G, Saur D. Eser S, et al. Among authors: alessi dr. Cancer Cell. 2013 Mar 18;23(3):406-20. doi: 10.1016/j.ccr.2013.01.023. Epub 2013 Feb 28. Cancer Cell. 2013. PMID: 23453624 Free article.
A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
Schönhuber N, Seidler B, Schuck K, Veltkamp C, Schachtler C, Zukowska M, Eser S, Feyerabend TB, Paul MC, Eser P, Klein S, Lowy AM, Banerjee R, Yang F, Lee CL, Moding EJ, Kirsch DG, Scheideler A, Alessi DR, Varela I, Bradley A, Kind A, Schnieke AE, Rodewald HR, Rad R, Schmid RM, Schneider G, Saur D. Schönhuber N, et al. Among authors: alessi dr. Nat Med. 2014 Nov;20(11):1340-1347. doi: 10.1038/nm.3646. Epub 2014 Oct 19. Nat Med. 2014. PMID: 25326799 Free PMC article.
PDK1, the master regulator of AGC kinase signal transduction.
Mora A, Komander D, van Aalten DM, Alessi DR. Mora A, et al. Among authors: alessi dr. Semin Cell Dev Biol. 2004 Apr;15(2):161-70. doi: 10.1016/j.semcdb.2003.12.022. Semin Cell Dev Biol. 2004. PMID: 15209375 Review.
Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse.
Sandu C, Artunc F, Palmada M, Rexhepaj R, Grahammer F, Hussain A, Yun C, Alessi DR, Lang F. Sandu C, et al. Among authors: alessi dr. Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G868-76. doi: 10.1152/ajpgi.00023.2006. Epub 2006 Jul 6. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16825708 Free article.
Reduced intestinal and renal amino acid transport in PDK1 hypomorphic mice.
Rexhepaj R, Grahammer F, Völkl H, Remy C, Wagner CA, Sandulache D, Artunc F, Henke G, Nammi S, Capasso G, Alessi DR, Lang F. Rexhepaj R, et al. Among authors: alessi dr. FASEB J. 2006 Nov;20(13):2214-22. doi: 10.1096/fj.05-5676com. FASEB J. 2006. PMID: 17077298 Free article.
308 results