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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 4
2003 5
2004 6
2005 5
2006 3
2007 4
2008 8
2009 5
2010 10
2011 6
2012 9
2013 12
2014 4
2015 6
2016 8
2017 8
2018 8
2019 5
2020 4
2021 6
2022 4
2023 5
2024 2

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128 results

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Page 1
Mitochondrial and cytosolic one-carbon metabolism is a targetable metabolic vulnerability in cisplatin-resistant ovarian cancer.
Wallace-Povirk A, O'Connor C, Dekhne AS, Bao X, Nayeen MJ, Schneider M, Katinas JM, Wong-Roushar J, Kim S, Polin L, Li J, Back JB, Dann CE, Gangjee A, Hou Z, Matherly LH. Wallace-Povirk A, et al. Among authors: gangjee a. Mol Cancer Ther. 2024 Feb 20. doi: 10.1158/1535-7163.MCT-23-0550. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38377173
Structural Characterization of 5-Substituted Pyrrolo[3,2-d]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Katinas JM, Nayeen MJ, Schneider M, Shah K, Fifer AN, Klapper LM, Sharma A, Thalluri K, Van Nieuwenhze MS, Hou Z, Gangjee A, Matherly LH, Dann CE 3rd. Katinas JM, et al. Among authors: gangjee a. Biochemistry. 2024 Feb 7. doi: 10.1021/acs.biochem.3c00613. Online ahead of print. Biochemistry. 2024. PMID: 38324671
Multitargeted 6-Substituted Thieno[2,3-d]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism.
Tong N, Wong-Roushar J, Wallace-Povirk A, Shah Y, Nyman MC, Katinas JM, Schneider M, O'Connor C, Bao X, Kim S, Li J, Hou Z, Matherly LH, Dann CE 3rd, Gangjee A. Tong N, et al. Among authors: gangjee a. ACS Pharmacol Transl Sci. 2023 Apr 26;6(5):748-770. doi: 10.1021/acsptsci.3c00020. eCollection 2023 May 12. ACS Pharmacol Transl Sci. 2023. PMID: 37200803 Free PMC article.
Correction: Novel Pyrrolo[3,2-d]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy.
Dekhne AS, Shah K, Ducker GS, Katinas JM, Wong-Roushar J, Nayeen MJ, Doshi A, Ning C, Bao X, Frühauf J, Liu J, Wallace-Povirk A, O'Connor C, Dzinic SH, White K, Kushner J, Kim S, Hüttemann M, Polin L, Rabinowitz JD, Li J, Hou Z, Dann CE, Gangjee A, Matherly LH. Dekhne AS, et al. Among authors: gangjee a. Mol Cancer Ther. 2023 Feb 1;22(2):287. doi: 10.1158/1535-7163.MCT-22-0766. Mol Cancer Ther. 2023. PMID: 36602953 No abstract available.
Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment.
Wallace-Povirk A, Rubinsak L, Malysa A, Dzinic SH, Ravindra M, Schneider M, Glassbrook J, O'Connor C, Hou Z, Kim S, Back J, Polin L, Morris RT, Gangjee A, Gibson H, Matherly LH. Wallace-Povirk A, et al. Among authors: gangjee a. Sci Rep. 2022 Jul 5;12(1):11346. doi: 10.1038/s41598-022-14788-5. Sci Rep. 2022. PMID: 35790779 Free PMC article.
128 results