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Diversity in immunogenomics: the value and the challenge.
Peng K, Safonova Y, Shugay M, Popejoy AB, Rodriguez OL, Breden F, Brodin P, Burkhardt AM, Bustamante C, Cao-Lormeau VM, Corcoran MM, Duffy D, Fuentes-Guajardo M, Fujita R, Greiff V, Jönsson VD, Liu X, Quintana-Murci L, Rossetti M, Xie J, Yaari G, Zhang W, Abedalthagafi MS, Adekoya KO, Ahmed RA, Chang WC, Gray C, Nakamura Y, Lees WD, Khatri P, Alachkar H, Scheepers C, Watson CT, Karlsson Hedestam GB, Mangul S. Peng K, et al. Among authors: alachkar h. Nat Methods. 2021 Jun;18(6):588-591. doi: 10.1038/s41592-021-01169-5. Nat Methods. 2021. PMID: 34002093 Free PMC article.
The era of immunogenomics/immunopharmacogenomics.
Zewde M, Kiyotani K, Park JH, Fang H, Yap KL, Yew PY, Alachkar H, Kato T, Mai TH, Ikeda Y, Matsuda T, Liu X, Ren L, Deng B, Harada M, Nakamura Y. Zewde M, et al. Among authors: alachkar h. J Hum Genet. 2018 Jul;63(8):865-875. doi: 10.1038/s10038-018-0468-1. Epub 2018 May 21. J Hum Genet. 2018. PMID: 29785006 Review.
Ancestral diversity is limited in published T cell receptor sequencing studies.
Huang YN, Peng K, Popejoy AB, Hu J, Nowicki TS, Gold SM, Quintana-Murci L, Fuentes-Guajardo M, Shugay M, Greiff V, Burkhardt AM, Alachkar H, Mangul S. Huang YN, et al. Among authors: alachkar h. Immunity. 2021 Oct 12;54(10):2177-2179. doi: 10.1016/j.immuni.2021.09.015. Immunity. 2021. PMID: 34644550 Free article. No abstract available.
Deciphering the TCR Repertoire to Solve the COVID-19 Mystery.
Gutierrez L, Beckford J, Alachkar H. Gutierrez L, et al. Among authors: alachkar h. Trends Pharmacol Sci. 2020 Aug;41(8):518-530. doi: 10.1016/j.tips.2020.06.001. Epub 2020 Jun 20. Trends Pharmacol Sci. 2020. PMID: 32576386 Free PMC article. Review.
Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients.
Yew PY, Alachkar H, Yamaguchi R, Kiyotani K, Fang H, Yap KL, Liu HT, Wickrema A, Artz A, van Besien K, Imoto S, Miyano S, Bishop MR, Stock W, Nakamura Y. Yew PY, et al. Among authors: alachkar h. Bone Marrow Transplant. 2015 Sep;50(9):1227-34. doi: 10.1038/bmt.2015.133. Epub 2015 Jun 8. Bone Marrow Transplant. 2015. PMID: 26052909 Free PMC article. Clinical Trial.
Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia.
Alachkar H, Fulton N, Sanford B, Malnassy G, Mutonga M, Larson RA, Bloomfield CD, Marcucci G, Nakamura Y, Stock W. Alachkar H, et al. Pharmacogenomics J. 2017 Jun;17(3):274-279. doi: 10.1038/tpj.2016.7. Epub 2016 Mar 29. Pharmacogenomics J. 2017. PMID: 27019981 Free PMC article. Clinical Trial.
85 results