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A patient-driven clinicogenomic partnership for metastatic prostate cancer.
Crowdis J, Balch S, Sterlin L, Thomas BS, Camp SY, Dunphy M, Anastasio E, Shah S, Damon AL, Ramos R, Sosa DM, Small IK, Tomson BN, Nguyen CM, McGillicuddy M, Chastain PS, He MX, Cheung ATM, Wankowicz S, Tewari AK, Kim D, AlDubayan SH, Dowdye A, Zola B, Nowak J, Manarite J, Gunn IH, Olson B, Lander ES, Painter CA, Wagle N, Van Allen EM. Crowdis J, et al. Among authors: aldubayan sh. Cell Genom. 2022 Sep 14;2(9):100169. doi: 10.1016/j.xgen.2022.100169. Epub 2022 Aug 19. Cell Genom. 2022. PMID: 36177448 Free PMC article.
Genomic evolution and chemoresistance in germ-cell tumours.
Taylor-Weiner A, Zack T, O'Donnell E, Guerriero JL, Bernard B, Reddy A, Han GC, AlDubayan S, Amin-Mansour A, Schumacher SE, Litchfield K, Turnbull C, Gabriel S, Beroukhim R, Getz G, Carter SL, Hirsch MS, Letai A, Sweeney C, Van Allen EM. Taylor-Weiner A, et al. Nature. 2016 Nov 30;540(7631):114-118. doi: 10.1038/nature20596. Nature. 2016. PMID: 27905446 Free PMC article.
Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations.
Huang FW, Mosquera JM, Garofalo A, Oh C, Baco M, Amin-Mansour A, Rabasha B, Bahl S, Mullane SA, Robinson BD, Aldubayan S, Khani F, Karir B, Kim E, Chimene-Weiss J, Hofree M, Romanel A, Osborne JR, Kim JW, Azabdaftari G, Woloszynska-Read A, Sfanos K, De Marzo AM, Demichelis F, Gabriel S, Van Allen EM, Mesirov J, Tamayo P, Rubin MA, Powell IJ, Garraway LA. Huang FW, et al. Cancer Discov. 2017 Sep;7(9):973-983. doi: 10.1158/2159-8290.CD-16-0960. Epub 2017 May 17. Cancer Discov. 2017. PMID: 28515055 Free PMC article.
Inherited DNA-Repair Defects in Colorectal Cancer.
AlDubayan SH, Giannakis M, Moore ND, Han GC, Reardon B, Hamada T, Mu XJ, Nishihara R, Qian Z, Liu L, Yurgelun MB, Syngal S, Garraway LA, Ogino S, Fuchs CS, Van Allen EM. AlDubayan SH, et al. Am J Hum Genet. 2018 Mar 1;102(3):401-414. doi: 10.1016/j.ajhg.2018.01.018. Epub 2018 Feb 22. Am J Hum Genet. 2018. PMID: 29478780 Free PMC article.
Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors.
AlDubayan SH, Pyle LC, Gamulin M, Kulis T, Moore ND, Taylor-Weiner A, Hamid AA, Reardon B, Wubbenhorst B, Godse R, Vaughn DJ, Jacobs LA, Meien S, Grgic M, Kastelan Z, Markt SC, Damrauer SM, Rader DJ, Kember RL, Loud JT, Kanetsky PA, Greene MH, Sweeney CJ, Kubisch C, Nathanson KL, Van Allen EM, Stewart DR, Lessel D; Regeneron Genetics Center (RGC) Research Team. AlDubayan SH, et al. JAMA Oncol. 2019 Apr 1;5(4):514-522. doi: 10.1001/jamaoncol.2018.6477. JAMA Oncol. 2019. PMID: 30676620 Free PMC article.
Germline Features Associated with Immune Infiltration in Solid Tumors.
Shahamatdar S, He MX, Reyna MA, Gusev A, AlDubayan SH, Van Allen EM, Ramachandran S. Shahamatdar S, et al. Among authors: aldubayan sh. Cell Rep. 2020 Mar 3;30(9):2900-2908.e4. doi: 10.1016/j.celrep.2020.02.039. Cell Rep. 2020. PMID: 32130895 Free PMC article.
Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma.
AlDubayan SH, Conway JR, Camp SY, Witkowski L, Kofman E, Reardon B, Han S, Moore N, Elmarakeby H, Salari K, Choudhry H, Al-Rubaish AM, Al-Sulaiman AA, Al-Ali AK, Taylor-Weiner A, Van Allen EM. AlDubayan SH, et al. JAMA. 2020 Nov 17;324(19):1957-1969. doi: 10.1001/jama.2020.20457. JAMA. 2020. PMID: 33201204 Free PMC article.
Integrated molecular drivers coordinate biological and clinical states in melanoma.
Conway JR, Dietlein F, Taylor-Weiner A, AlDubayan S, Vokes N, Keenan T, Reardon B, He MX, Margolis CA, Weirather JL, Haq R, Schilling B, Stephen Hodi F, Schadendorf D, Liu D, Van Allen EM. Conway JR, et al. Nat Genet. 2020 Dec;52(12):1373-1383. doi: 10.1038/s41588-020-00739-1. Epub 2020 Nov 23. Nat Genet. 2020. PMID: 33230298 Free PMC article.
Evaluating the molecular diagnostic yield of joint genotyping-based approach for detecting rare germline pathogenic and putative loss-of-function variants.
Camp SY, Kofman E, Reardon B, Moore ND, Al-Rubaish AM, Aljumaan M, Al-Ali AK, Van Allen EM, Taylor-Weiner A, AlDubayan SH. Camp SY, et al. Among authors: aldubayan sh. Genet Med. 2021 May;23(5):918-926. doi: 10.1038/s41436-020-01074-w. Epub 2021 Feb 2. Genet Med. 2021. PMID: 33531667 Free PMC article.
Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer.
Tewari AK, Cheung ATM, Crowdis J, Conway JR, Camp SY, Wankowicz SA, Livitz DG, Park J, Lis RT, Bosma-Moody A, He MX, AlDubayan SH, Zhang Z, McKay RR, Leshchiner I, Brown M, Balk SP, Getz G, Taplin ME, Van Allen EM. Tewari AK, et al. Among authors: aldubayan sh. Cell Rep. 2021 Sep 7;36(10):109665. doi: 10.1016/j.celrep.2021.109665. Cell Rep. 2021. PMID: 34496240 Free article.
40 results