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Rational design, synthesis, biological evaluation, and molecular modeling of novel naphthamide derivatives possessing potent, reversible, and competitive inhibitory mode of action over human monoamine oxidase.
Elkamhawy A, Oh JM, Kim M, El-Halaby LO, Abdellattif MH, Al-Karmalawy AA, Kim H, Lee K. Elkamhawy A, et al. Among authors: al karmalawy aa. Mol Divers. 2024 May 10. doi: 10.1007/s11030-024-10841-9. Online ahead of print. Mol Divers. 2024. PMID: 38727994
Coenzyme Q10 mitigates cadmium cardiotoxicity by downregulating NF-κB/NLRP3 inflammasome axis and attenuating oxidative stress in mice.
Antar SA, Abdo W, Helal AI, Abduh MS, Hakami ZH, Germoush MO, Alsulimani A, Al-Noshokaty TM, El-Dessouki AM, ElMahdy MK, Elgebaly HA, Al-Karmalawy AA, Mahmoud AM. Antar SA, et al. Among authors: al karmalawy aa. Life Sci. 2024 May 4;348:122688. doi: 10.1016/j.lfs.2024.122688. Online ahead of print. Life Sci. 2024. PMID: 38710284
Multi-target rational design and synthesis of novel diphenyl-tethered pyrazolopyrimidines targeting EGFR and topoisomerase II with potential DNA intercalation and apoptosis induction.
Gaber AA, Abo Elmaaty A, Sharaky M, Mosa AA, Yahya Abdullah Alzahrani A, Shaaban S, Eldehna WM, Al-Karmalawy AA. Gaber AA, et al. Among authors: al karmalawy aa. Bioorg Chem. 2024 Apr;145:107223. doi: 10.1016/j.bioorg.2024.107223. Epub 2024 Feb 17. Bioorg Chem. 2024. PMID: 38387399
119 results