Al-Karmalawy AA - Search Results

1

Design and synthesis of new spirooxindole candidates and their selenium nanoparticles as potential dual Topo I/II inhibitors, DNA intercalators, and apoptotic inducers.

El-Kalyoubi S, Khalifa MM, Abo-Elfadl MT, El-Sayed AA, Elkamhawy A, Lee K, Al-Karmalawy AA. El-Kalyoubi S, et al. J Enzyme Inhib Med Chem. 2023 Aug 17;38(1):2242714. doi: 10.1080/14756366.2023.2242714. J Enzyme Inhib Med Chem. 2023. PMID: 37592917 Free PMC article.

2

Effect of Vitamin D supplementation in patients with liver cirrhosis having spontaneous bacterial peritonitis: a randomized controlled study.

Mohamed AA, Al-Karmalawy AA, El-Kholy AA, El-Damas DA, Abostate HM, Mostafa SM, Hamada M, Khalik Elkady MA, Hassan Y, Al-Hussain E, Khalil MG, Badawy I, Elebeedy D, Alsfouk BA, Shaheenl MM. Mohamed AA, et al. Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):6908-6919. doi: 10.26355/eurrev_202111_27239. Eur Rev Med Pharmacol Sci. 2021. PMID: 34859852 Free article. Clinical Trial.

3

Coronavirus Disease (COVID-19) Control between Drug Repurposing and Vaccination: A Comprehensive Overview.

Al-Karmalawy AA, Soltane R, Abo Elmaaty A, Tantawy MA, Antar SA, Yahya G, Chrouda A, Pashameah RA, Mustafa M, Abu Mraheil M, Mostafa A. Al-Karmalawy AA, et al. Vaccines (Basel). 2021 Nov 12;9(11):1317. doi: 10.3390/vaccines9111317. Vaccines (Basel). 2021. PMID: 34835248 Free PMC article. Review.

4

Design and discovery of new 1,2,4-triazolo[4,3-c]quinazolines as potential DNA intercalators and topoisomerase II inhibitors.

Alesawy MS, Al-Karmalawy AA, Elkaeed EB, Alswah M, Belal A, Taghour MS, Eissa IH. Alesawy MS, et al. Arch Pharm (Weinheim). 2021 Mar;354(3):e2000237. doi: 10.1002/ardp.202000237. Epub 2020 Nov 23. Arch Pharm (Weinheim). 2021. PMID: 33226150

5

Design and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR Studies.

Ma C, Taghour MS, Belal A, Mehany ABM, Mostafa N, Nabeeh A, Eissa IH, Al-Karmalawy AA. Ma C, et al. Front Chem. 2021 Sep 22;9:725135. doi: 10.3389/fchem.2021.725135. eCollection 2021. Front Chem. 2021. PMID: 34631658 Free PMC article.

6

Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies.

Khalifa MM, Al-Karmalawy AA, Elkaeed EB, Nafie MS, Tantawy MA, Eissa IH, Mahdy HA. Khalifa MM, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):299-314. doi: 10.1080/14756366.2021.2007905. J Enzyme Inhib Med Chem. 2022. PMID: 34894955 Free PMC article.

7

Revisiting activity of some glucocorticoids as a potential inhibitor of SARS-CoV-2 main protease: theoretical study.

Elmaaty AA, Alnajjar R, Hamed MIA, Khattab M, Khalifa MM, Al-Karmalawy AA. Elmaaty AA, et al. RSC Adv. 2021 Mar 9;11(17):10027-10042. doi: 10.1039/d0ra10674g. eCollection 2021 Mar 5. RSC Adv. 2021. PMID: 35423530 Free PMC article.

8

Ligand-based design and synthesis of N'-Benzylidene-3,4-dimethoxybenzohydrazide derivatives as potential antimicrobial agents; evaluation by in vitro, in vivo, and in silico approaches with SAR studies.

Ezz Eldin RR, Saleh MA, Alotaibi MH, Alsuair RK, Alzahrani YA, Alshehri FA, Mohamed AF, Hafez SM, Althoqapy AA, Khirala SK, Amin MM, A F Y, AbdElwahab AH, Alesawy MS, Elmaaty AA, Al-Karmalawy AA. Ezz Eldin RR, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1098-1119. doi: 10.1080/14756366.2022.2063282. J Enzyme Inhib Med Chem. 2022. PMID: 35430934 Free PMC article.

9

Design, synthesis and molecular docking of new fused 1H-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors.

Belal A, Abdel Gawad NM, Mehany ABM, Abourehab MAS, Elkady H, Al-Karmalawy AA, Ismael AS. Belal A, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1884-1902. doi: 10.1080/14756366.2022.2096019. J Enzyme Inhib Med Chem. 2022. PMID: 35801486 Free PMC article.

10

Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease.

Elagawany M, Elmaaty AA, Mostafa A, Abo Shama NM, Santali EY, Elgendy B, Al-Karmalawy AA. Elagawany M, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2112-2132. doi: 10.1080/14756366.2022.2105322. J Enzyme Inhib Med Chem. 2022. PMID: 35912578 Free PMC article.

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