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Exploring the impact of the PNPLA3 I148M variant on primary human hepatic stellate cells using 3D extracellular matrix models.
Caon E, Martins M, Hodgetts H, Blanken L, Vilia MG, Levi A, Thanapirom K, Al-Akkad W, Abu-Hanna J, Baselli G, Hall AR, Luong TV, Taanman JW, Vacca M, Valenti L, Romeo S, Mazza G, Pinzani M, Rombouts K. Caon E, et al. Among authors: al akkad w. J Hepatol. 2024 Feb 15:S0168-8278(24)00110-7. doi: 10.1016/j.jhep.2024.01.032. Online ahead of print. J Hepatol. 2024. PMID: 38365182 Free article.
Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS.
Pallett LJ, Swadling L, Diniz M, Maini AA, Schwabenland M, Gasull AD, Davies J, Kucykowicz S, Skelton JK, Thomas N, Schmidt NM, Amin OE, Gill US, Stegmann KA, Burton AR, Stephenson E, Reynolds G, Whelan M, Sanchez J, de Maeyer R, Thakker C, Suveizdyte K, Uddin I, Ortega-Prieto AM, Grant C, Froghi F, Fusai G, Lens S, Pérez-Del-Pulgar S, Al-Akkad W, Mazza G, Noursadeghi M, Akbar A, Kennedy PTF, Davidson BR, Prinz M, Chain BM, Haniffa M, Gilroy DW, Dorner M, Bengsch B, Schurich A, Maini MK. Pallett LJ, et al. Among authors: al akkad w. Nature. 2023 Feb;614(7947):334-342. doi: 10.1038/s41586-022-05645-6. Epub 2023 Jan 25. Nature. 2023. PMID: 36697826
Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance.
Al-Akkad W, Acedo P, Vilia MG, Frenguelli L, Ney A, Rodriguez-Hernandez I, Labib PL, Tamburrino D, Spoletini G, Hall AR, Canestrari S, Osnato A, Garcia-Bernardo J, Sejour L, Vassileva V, Vlachos IS, Fusai G, Luong TV, Whittaker SR, Pereira SP, Vallier L, Pinzani M, Rombouts K, Mazza G. Al-Akkad W, et al. Cells. 2022 Nov 17;11(22):3652. doi: 10.3390/cells11223652. Cells. 2022. PMID: 36429078 Free PMC article.
Pharmacokinetic Characterisation and Comparison of Bioavailability of Intranasal Fentanyl, Transmucosal, and Intravenous Administration through a Three-Way Crossover Study in 24 Healthy Volunteers.
Nardi-Hiebl S, Ndieyira JW, Al Enzi Y, Al Akkad W, Koch T, Geldner G, Reyher C, Eberhart LHJ. Nardi-Hiebl S, et al. Among authors: al akkad w. Pain Res Manag. 2021 Nov 29;2021:2887773. doi: 10.1155/2021/2887773. eCollection 2021. Pain Res Manag. 2021. PMID: 34880961 Free PMC article. Clinical Trial.
Cirrhotic Human Liver Extracellular Matrix 3D Scaffolds Promote Smad-Dependent TGF-β1 Epithelial Mesenchymal Transition.
Mazza G, Telese A, Al-Akkad W, Frenguelli L, Levi A, Marrali M, Longato L, Thanapirom K, Vilia MG, Lombardi B, Crowley C, Crawford M, Karsdal MA, Leeming DJ, Marrone G, Bottcher K, Robinson B, Del Rio Hernandez A, Tamburrino D, Spoletini G, Malago M, Hall AR, Godovac-Zimmermann J, Luong TV, De Coppi P, Pinzani M, Rombouts K. Mazza G, et al. Among authors: al akkad w. Cells. 2019 Dec 28;9(1):83. doi: 10.3390/cells9010083. Cells. 2019. PMID: 31905709 Free PMC article.
Decellularized Human Gut as a Natural 3D Platform for Research in Intestinal Fibrosis.
Giuffrida P, Curti M, Al-Akkad W, Biel C, Crowley C, Frenguelli L, Telese A, Hall A, Tamburrino D, Spoletini G, Fusai G, Tinozzi FP, Pietrabissa A, Corazza GR, De Coppi P, Pinzani M, Di Sabatino A, Rombouts K, Mazza G. Giuffrida P, et al. Among authors: al akkad w. Inflamm Bowel Dis. 2019 Oct 18;25(11):1740-1750. doi: 10.1093/ibd/izz115. Inflamm Bowel Dis. 2019. PMID: 31199863
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