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Yes-Associated Protein (Yap) Is Up-Regulated in Heart Failure and Promotes Cardiac Fibroblast Proliferation.
Sharifi-Sanjani M, Berman M, Goncharov D, Alhamaydeh M, Avolio TG, Baust J, Chang B, Kobir A, Ross M, St Croix C, Nouraie SM, McTiernan CF, Moravec CS, Goncharova E, Al Ghouleh I. Sharifi-Sanjani M, et al. Among authors: al ghouleh i. Int J Mol Sci. 2021 Jun 7;22(11):6164. doi: 10.3390/ijms22116164. Int J Mol Sci. 2021. PMID: 34200497 Free PMC article.
Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1.
Csányi G, Yao M, Rodríguez AI, Al Ghouleh I, Sharifi-Sanjani M, Frazziano G, Huang X, Kelley EE, Isenberg JS, Pagano PJ. Csányi G, et al. Among authors: al ghouleh i. Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2966-73. doi: 10.1161/ATVBAHA.112.300031. Epub 2012 Oct 18. Arterioscler Thromb Vasc Biol. 2012. PMID: 23087362 Free PMC article.
The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1.
Meijles DN, Sahoo S, Al Ghouleh I, Amaral JH, Bienes-Martinez R, Knupp HE, Attaran S, Sembrat JC, Nouraie SM, Rojas MM, Novelli EM, Gladwin MT, Isenberg JS, Cifuentes-Pagano E, Pagano PJ. Meijles DN, et al. Among authors: al ghouleh i. Sci Signal. 2017 Oct 17;10(501):eaaj1784. doi: 10.1126/scisignal.aaj1784. Sci Signal. 2017. PMID: 29042481 Free PMC article.
Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension.
Negi V, Yang J, Speyer G, Pulgarin A, Handen A, Zhao J, Tai YY, Tang Y, Culley MK, Yu Q, Forsythe P, Gorelova A, Watson AM, Al Aaraj Y, Satoh T, Sharifi-Sanjani M, Rajaratnam A, Sembrat J, Provencher S, Yin X, Vargas SO, Rojas M, Bonnet S, Torrino S, Wagner BK, Schreiber SL, Dai M, Bertero T, Al Ghouleh I, Kim S, Chan SY. Negi V, et al. Among authors: al ghouleh i. Sci Adv. 2021 Oct 22;7(43):eabh3794. doi: 10.1126/sciadv.abh3794. Epub 2021 Oct 20. Sci Adv. 2021. PMID: 34669463 Free PMC article.
24 results