Aitken SM - Search Results

1

Development of a continuous assay and steady-state characterization of Escherichia coli threonine synthase.

Morneau DJ, Abouassaf E, Skanes JE, Aitken SM. Morneau DJ, et al. Among authors: aitken sm. Anal Biochem. 2012 Apr 1;423(1):78-85. doi: 10.1016/j.ab.2012.01.004. Epub 2012 Jan 18. Anal Biochem. 2012. PMID: 22289691

2

Interconversion of a pair of active-site residues in Escherichia coli cystathionine gamma-synthase, E. coli cystathionine beta-lyase, and Saccharomyces cerevisiae cystathionine gamma-lyase and development of tools for the investigation of their mechanisms and reaction specificity.

Farsi A, Lodha PH, Skanes JE, Los H, Kalidindi N, Aitken SM. Farsi A, et al. Among authors: aitken sm. Biochem Cell Biol. 2009 Apr;87(2):445-57. doi: 10.1139/o08-144. Biochem Cell Biol. 2009. PMID: 19370061

3

Identification of cystathionine γ-synthase and threonine synthase from Cicer arietinum and Lens culinaris.

Morneau DJ, Jaworski AF, Aitken SM. Morneau DJ, et al. Among authors: aitken sm. Biochem Cell Biol. 2013 Apr;91(2):95-101. doi: 10.1139/bcb-2012-0096. Epub 2012 Nov 12. Biochem Cell Biol. 2013. PMID: 23527638

4

The enzymes of the transsulfuration pathways: active-site characterizations.

Aitken SM, Lodha PH, Morneau DJ. Aitken SM, et al. Biochim Biophys Acta. 2011 Nov;1814(11):1511-7. doi: 10.1016/j.bbapap.2011.03.006. Epub 2011 Mar 22. Biochim Biophys Acta. 2011. PMID: 21435402 Review.

5

Characterization of the side-chain hydroxyl moieties of residues Y56, Y111, Y238, Y338, and S339 as determinants of specificity in E. coli cystathionine β-lyase.

Lodha PH, Aitken SM. Lodha PH, et al. Among authors: aitken sm. Biochemistry. 2011 Nov 15;50(45):9876-85. doi: 10.1021/bi201090n. Epub 2011 Oct 25. Biochemistry. 2011. PMID: 21958132

6

Escherichia coli cystathionine gamma-synthase does not obey ping-pong kinetics. Novel continuous assays for the elimination and substitution reactions.

Aitken SM, Kim DH, Kirsch JF. Aitken SM, et al. Biochemistry. 2003 Sep 30;42(38):11297-306. doi: 10.1021/bi035107o. Biochemistry. 2003. PMID: 14503880

7

Exploration of the active site of Escherichia coli cystathionine γ-synthase.

Jaworski AF, Lodha PH, Manders AL, Aitken SM. Jaworski AF, et al. Among authors: aitken sm. Protein Sci. 2012 Nov;21(11):1662-71. doi: 10.1002/pro.2135. Protein Sci. 2012. PMID: 22855027 Free PMC article.

8

Kinetic characterization of recombinant human cystathionine beta-synthase purified from E. coli.

Belew MS, Quazi FI, Willmore WG, Aitken SM. Belew MS, et al. Among authors: aitken sm. Protein Expr Purif. 2009 Apr;64(2):139-45. doi: 10.1016/j.pep.2008.10.012. Epub 2008 Oct 30. Protein Expr Purif. 2009. PMID: 19010420

9

Kinetics of the yeast cystathionine beta-synthase forward and reverse reactions: continuous assays and the equilibrium constant for the reaction.

Aitken SM, Kirsch JF. Aitken SM, et al. Biochemistry. 2003 Jan 21;42(2):571-8. doi: 10.1021/bi026681n. Biochemistry. 2003. PMID: 12525186

10

Exploration of structure-function relationships in Escherichia coli cystathionine γ-synthase and cystathionine β-lyase via chimeric constructs and site-specific substitutions.

Manders AL, Jaworski AF, Ahmed M, Aitken SM. Manders AL, et al. Among authors: aitken sm. Biochim Biophys Acta. 2013 Jun;1834(6):1044-53. doi: 10.1016/j.bbapap.2013.02.036. Epub 2013 Mar 5. Biochim Biophys Acta. 2013. PMID: 23470500

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