Aitha M - Search Results

1

Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7.

Bergstrom A, Katko A, Adkins Z, Hill J, Cheng Z, Burnett M, Yang H, Aitha M, Mehaffey MR, Brodbelt JS, Tehrani KHME, Martin NI, Bonomo RA, Page RC, Tierney DL, Fast W, Wright GD, Crowder MW. Bergstrom A, et al. Among authors: aitha m. ACS Infect Dis. 2018 Feb 9;4(2):135-145. doi: 10.1021/acsinfecdis.7b00106. Epub 2017 Nov 9. ACS Infect Dis. 2018. PMID: 29091730 Free PMC article.

2

Mechanistic and spectroscopic studies of metallo-β-lactamase NDM-1.

Yang H, Aitha M, Hetrick AM, Richmond TK, Tierney DL, Crowder MW. Yang H, et al. Among authors: aitha m. Biochemistry. 2012 May 8;51(18):3839-47. doi: 10.1021/bi300056y. Epub 2012 Apr 25. Biochemistry. 2012. PMID: 22482529

3

Spectroscopic and mechanistic studies of heterodimetallic forms of metallo-β-lactamase NDM-1.

Yang H, Aitha M, Marts AR, Hetrick A, Bennett B, Crowder MW, Tierney DL. Yang H, et al. Among authors: aitha m. J Am Chem Soc. 2014 May 21;136(20):7273-85. doi: 10.1021/ja410376s. Epub 2014 May 12. J Am Chem Soc. 2014. PMID: 24754678 Free PMC article.

4

Biochemical, mechanistic, and spectroscopic characterization of metallo-β-lactamase VIM-2.

Aitha M, Marts AR, Bergstrom A, Møller AJ, Moritz L, Turner L, Nix JC, Bonomo RA, Page RC, Tierney DL, Crowder MW. Aitha M, et al. Biochemistry. 2014 Nov 25;53(46):7321-31. doi: 10.1021/bi500916y. Epub 2014 Nov 13. Biochemistry. 2014. PMID: 25356958 Free PMC article.

5

Investigating the position of the hairpin loop in New Delhi metallo-β-lactamase, NDM-1, during catalysis and inhibitor binding.

Aitha M, Moller AJ, Sahu ID, Horitani M, Tierney DL, Crowder MW. Aitha M, et al. J Inorg Biochem. 2016 Mar;156:35-9. doi: 10.1016/j.jinorgbio.2015.10.011. Epub 2015 Oct 22. J Inorg Biochem. 2016. PMID: 26717260 Free PMC article.

6

A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases.

Lisa MN, Palacios AR, Aitha M, González MM, Moreno DM, Crowder MW, Bonomo RA, Spencer J, Tierney DL, Llarrull LI, Vila AJ. Lisa MN, et al. Among authors: aitha m. Nat Commun. 2017 Sep 14;8(1):538. doi: 10.1038/s41467-017-00601-9. Nat Commun. 2017. PMID: 28912448 Free PMC article.

7

Meropenem and chromacef intermediates observed in IMP-25 metallo-β-lactamase-catalyzed hydrolysis.

Oelschlaeger P, Aitha M, Yang H, Kang JS, Zhang AL, Liu EM, Buynak JD, Crowder MW. Oelschlaeger P, et al. Among authors: aitha m. Antimicrob Agents Chemother. 2015 Jul;59(7):4326-30. doi: 10.1128/AAC.04409-14. Epub 2015 Apr 27. Antimicrob Agents Chemother. 2015. PMID: 25918145 Free PMC article.

8

Metal Ion Dependence of the Matrix Metalloproteinase-1 Mechanism.

Yang H, Makaroff K, Paz N, Aitha M, Crowder MW, Tierney DL. Yang H, et al. Among authors: aitha m. Biochemistry. 2015 Jun 16;54(23):3631-9. doi: 10.1021/acs.biochem.5b00379. Epub 2015 Jun 8. Biochemistry. 2015. PMID: 26018933

9

Probing substrate binding to the metal binding sites in metallo-β-lactamase L1 during catalysis.

Aitha M, Al-Adbul-Wahid S, Tierney DL, Crowder MW. Aitha M, et al. Medchemcomm. 2016 Jan 1;7(1):194-201. doi: 10.1039/C5MD00358J. Epub 2016 Jan 4. Medchemcomm. 2016. PMID: 27087914 Free PMC article.

10

Conformational dynamics of metallo-β-lactamase CcrA during catalysis investigated by using DEER spectroscopy.

Aitha M, Moritz L, Sahu ID, Sanyurah O, Roche Z, McCarrick R, Lorigan GA, Bennett B, Crowder MW. Aitha M, et al. J Biol Inorg Chem. 2015 Apr;20(3):585-94. doi: 10.1007/s00775-015-1244-8. Epub 2015 Feb 10. J Biol Inorg Chem. 2015. PMID: 25827593 Free PMC article.

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