Ainscough JFX - Search Results

1

Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca²⁺ Handling After Pressure Overload.

Bartoli F, Bailey MA, Rode B, Mateo P, Antigny F, Bedouet K, Gerbaud P, Gosain R, Plante J, Norman K, Gomez S, Lefebvre F, Rucker-Martin C, Ainscough JFX, Kearney MT, Bruns AF, Shi J, Appleby HL, Young RS, Shawer HM, Debant M, Gomez AM, Beech DJ, Foster R, Benitah JP, Sabourin J. Bartoli F, et al. Among authors: ainscough jfx. Circulation. 2020 Jan 21;141(3):199-216. doi: 10.1161/CIRCULATIONAHA.118.038891. Epub 2020 Jan 7. Circulation. 2020. PMID: 31906693 Free PMC article.

2

Constitutively active TRPC channels of adipocytes confer a mechanism for sensing dietary fatty acids and regulating adiponectin.

Sukumar P, Sedo A, Li J, Wilson LA, O'Regan D, Lippiat JD, Porter KE, Kearney MT, Ainscough JF, Beech DJ. Sukumar P, et al. Circ Res. 2012 Jul 6;111(2):191-200. doi: 10.1161/CIRCRESAHA.112.270751. Epub 2012 Jun 5. Circ Res. 2012. PMID: 22668831 Free PMC article.

3

TRPC5 ion channel permeation promotes weight gain in hypercholesterolaemic mice.

Rode B, Yuldasheva NY, Baxter PD, Sedo A, Ainscough JF, Shires M, Kearney MT, Bailey MA, Wheatcroft SB, Beech DJ. Rode B, et al. Sci Rep. 2019 Jan 28;9(1):773. doi: 10.1038/s41598-018-37299-8. Sci Rep. 2019. PMID: 30692584 Free PMC article.

4

A differential role of macrophage TRPM2 channels in Ca²⁺ signaling and cell death in early responses to H₂O₂.

Zou J, Ainscough JF, Yang W, Sedo A, Yu SP, Mei ZZ, Sivaprasadarao A, Beech DJ, Jiang LH. Zou J, et al. Am J Physiol Cell Physiol. 2013 Jul 1;305(1):C61-9. doi: 10.1152/ajpcell.00390.2012. Epub 2013 Apr 17. Am J Physiol Cell Physiol. 2013. PMID: 23596170 Free article.

5

Piezo1 integration of vascular architecture with physiological force.

Li J, Hou B, Tumova S, Muraki K, Bruns A, Ludlow MJ, Sedo A, Hyman AJ, McKeown L, Young RS, Yuldasheva NY, Majeed Y, Wilson LA, Rode B, Bailey MA, Kim HR, Fu Z, Carter DA, Bilton J, Imrie H, Ajuh P, Dear TN, Cubbon RM, Kearney MT, Prasad RK, Evans PC, Ainscough JF, Beech DJ. Li J, et al. Nature. 2014 Nov 13;515(7526):279-282. doi: 10.1038/nature13701. Epub 2014 Aug 10. Nature. 2014. PMID: 25119035 Free PMC article.

6

Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism.

Bageghni SA, Hemmings KE, Zava N, Denton CP, Porter KE, Ainscough JFX, Drinkhill MJ, Turner NA. Bageghni SA, et al. Among authors: ainscough jfx. FASEB J. 2018 Sep;32(9):4941-4954. doi: 10.1096/fj.201701455RR. Epub 2018 Mar 30. FASEB J. 2018. PMID: 29601781 Free PMC article.

7

TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia.

Ye M, Yang W, Ainscough JF, Hu XP, Li X, Sedo A, Zhang XH, Zhang X, Chen Z, Li XM, Beech DJ, Sivaprasadarao A, Luo JH, Jiang LH. Ye M, et al. Cell Death Dis. 2014 Nov 27;5(11):e1541. doi: 10.1038/cddis.2014.494. Cell Death Dis. 2014. PMID: 25429618 Free PMC article.

8

A state of reversible compensated ventricular dysfunction precedes pathological remodelling in response to cardiomyocyte-specific activity of angiotensin II type-1 receptor in mice.

Frentzou GA, Drinkhill MJ, Turner NA, Ball SG, Ainscough JF. Frentzou GA, et al. Dis Model Mech. 2015 Aug 1;8(8):783-94. doi: 10.1242/dmm.019174. Epub 2015 Jun 18. Dis Model Mech. 2015. PMID: 26092119 Free PMC article.

9

Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction.

Bageghni SA, Hemmings KE, Yuldasheva NY, Maqbool A, Gamboa-Esteves FO, Humphreys NE, Jackson MS, Denton CP, Francis S, Porter KE, Ainscough JF, Pinteaux E, Drinkhill MJ, Turner NA. Bageghni SA, et al. JCI Insight. 2019 Aug 8;5(17):e125074. doi: 10.1172/jci.insight.125074. JCI Insight. 2019. PMID: 31393855 Free PMC article.

10

Angiotensin II type-1 receptor activation in the adult heart causes blood pressure-independent hypertrophy and cardiac dysfunction.

Ainscough JF, Drinkhill MJ, Sedo A, Turner NA, Brooke DA, Balmforth AJ, Ball SG. Ainscough JF, et al. Cardiovasc Res. 2009 Feb 15;81(3):592-600. doi: 10.1093/cvr/cvn230. Epub 2008 Aug 14. Cardiovasc Res. 2009. PMID: 18703536

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